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What are the main application fields of 1,2,3-trifluoro-5- (trans-4- (2- (trans-4-propylcyclohexyl) ethyl) cyclohexyl) benzene
1,2,3-Triazine-5- (trans-4- (2 - (trans-4-butylcyclohexyl) ethyl) cyclohexyl) benzene has shown diverse and important applications in the fields of medicine and materials science.
In the field of medicine, due to its unique molecular structure, it has a good fit with specific biological targets. For example, studies have found that it has a targeted effect on certain cancer cell-specific receptors, can precisely bind and block cancer cell signaling pathways, inhibit cancer cell proliferation and spread, and open up new ideas for the research and development of anti-cancer drugs. It is expected to become a key active ingredient of new anti-cancer drugs. In addition, it also has a regulatory function on targets related to neurodegenerative diseases, or plays a positive role in the treatment of neurodegenerative diseases such as Alzheimer's disease and Parkinson's disease.
In the field of materials science, with its special combination of rigid and flexible structures, it can be used as a key component of liquid crystal materials. When applied to liquid crystal displays, it can significantly improve display performance, such as enhancing the order of liquid crystal molecules, speeding up the response speed, making the picture switch faster and clearer, helping to improve the resolution and contrast of liquid crystal displays, and promoting the development of display technology. Moreover, the introduction of polymer materials can improve the mechanical properties of materials, enhance the strength and toughness of materials, and expand the application in aerospace, automobile manufacturing and other fields that require strict material properties.
What are the physical properties of 1,2,3-trifluoro-5- (trans-4- (2- (trans-4-propylcyclohexyl) ethyl) cyclohexyl) benzene
1% 2C2% 2C3-tribromo-5- (trans-4- (2- (trans-4-propylcyclohexyl) ethyl) cyclohexyl) benzene This compound has the following physical properties:
Its appearance is mostly colorless and transparent to light yellow viscous liquid. In the field of organic synthesis, it often exhibits unique properties due to its special structure. In terms of phase characteristics, it has certain liquid crystal characteristics and has a relatively stable mesocrystalline phase temperature range. It can exhibit a liquid crystal state within a specific temperature range. This temperature range makes it have application potential in display materials and other fields.
Discuss solubility. The compound exhibits good solubility in common organic solvents such as toluene and dichloromethane, and can be mutually soluble with these organic solvents in a certain proportion. With this property, it can be effectively dispersed as a solute when preparing related materials by solution method. However, in water, it is almost insoluble due to its hydrophobicity.
Discuss melting point and boiling point. Due to the complex cyclic structure in the molecule and the interaction of alkyl chains, its melting point is relatively moderate, while the boiling point is high, so as to ensure that the compound can maintain a relatively stable liquid or liquid crystal state within a certain temperature range, and is not prone to rapid phase transition due to temperature fluctuations. This relatively stable phase property makes it play an important role in some application scenarios that require temperature stability, such as the manufacturing of liquid crystal display components, which helps to maintain the stability and reliability of display performance.
What are the chemical properties of 1,2,3-trifluoro-5- (trans-4- (2- (trans-4-propylcyclohexyl) ethyl) cyclohexyl) benzene
1% 2C2% 2C3-tribromo-5- (trans-4- (2 - (trans-4-propylcyclohexyl) ethyl) cyclohexyl) benzene, the chemical properties of this compound are quite complex. The benzene ring, cyclohexyl and bromine atoms contained in its structure all affect its properties.
The benzene ring has a conjugated system, which endows the compound with certain stability and aromaticity. The introduction of bromine atoms significantly changes the electron cloud distribution of the molecule. Due to the high electronegativity of bromine, the electron cloud density of the benzene ring will decrease, which in turn affects the reactivity of the compound. And bromine atoms can participate in various chemical reactions such as nucleophilic substitution and elimination. The cyclohexyl structure in
molecules has a great influence on the spatial structure and physical properties of compounds due to the existence of its chair or boat conformations. For example, different conformations will lead to differences in intermolecular forces, which affect physical properties such as melting point and boiling point. The existence of trans structures also plays a role in the spatial arrangement and properties of molecules.
In terms of solubility, because there are both polar bromine atoms and non-polar hydrocarbon structures in the molecule, its solubility may be between polar and non-polar solvents. In terms of chemical reactivity, typical reactions such as halogenated hydrocarbons can occur due to the activity of bromine atoms, and new compounds can be formed by reacting with nucleophiles. At the same time, the presence of benzene rings also enables them to participate in the characteristic reactions of aromatic compounds, such as electrophilic substitution reactions. The chemical properties of this compound are determined by its unique molecular structure, and may have certain application potential in organic synthesis, materials science and other fields.
What is the synthesis method of 1,2,3-trifluoro-5- (trans-4- (2- (trans-4-propylcyclohexyl) ethyl) cyclohexyl) benzene
To prepare 1% 2C2% 2C3-tribromo-5- (trans-4- (2 - (trans-4-butylcyclohexyl) ethyl) cyclohexyl) benzene, the following method can be used:
Start with trans-4-butylcyclohexylbenzoic acid as the starting material, and first heat it with sulfinyl chloride to obtain trans-4-butylcyclohexylbenzoyl chloride. In this process, sulfinyl chloride interacts with acid, chloro-carboxyl group forms acid chloride, and sulfur dioxide and hydrogen chloride gas escape at the same time.
Next, the obtained trans-4-butylcyclohexylbenzoyl chloride is reacted with trans-4 - (2-hydroxyethyl) cyclohexane under the catalysis of a base. The base can be selected from pyridine or the like. Under this condition, the acid chloride is condensed with the hydroxyl group, and the hydrogen chloride is removed to obtain the trans-4 - (2 - (trans-4-butylcyclohexyl) acetoxy) cyclohexane.
Then, the above product is treated with a reducing agent such as lithium aluminum hydride, and the ester group is reduced to an alcohol to obtain the trans-4- (2- (trans-4-butylcyclohexyl) ethyl) cyclohexanol. In this reduction step, lithium aluminum hydride provides hydrogen negative ions to attack the carbonyl carbon of the ester group. After a series of changes, the final alcohol product is obtained.
Then the trans-4- (2- (trans-4-butylcyclohexyl) ethyl) cyclohexanol is subjected to a Fu-gram alkylation reaction with p-bromobenzene. Using anhydrous aluminum trichloride as a catalyst, in a suitable solvent, alcohol first forms carbocation, and then attacks the benzene ring to obtain 5- (trans-4- (2- (trans-4-butylcyclohexyl) ethyl) cyclohexyl) benzene.
Finally, 5- (trans-4- (2- (trans-4-butylcyclohexyl) ethyl) cyclohexyl) benzene is reacted with bromine under appropriate conditions, catalyzed by iron powder or the like, and the bromine atom selectively replaces the hydrogen atom on the benzene ring to obtain 1% 2C2% 2C3-tribromo-5- (trans-4- (2 - (trans-4-butylcyclohexyl) ethyl) cyclohexyl) benzene. Each step requires careful control of reaction conditions, such as temperature, reactant ratio, and reaction time, to ensure high yield and purity.
What is the price range of 1,2,3-trifluoro-5- (trans-4- (2- (trans-4-propylcyclohexyl) ethyl) cyclohexyl) benzene in the market?
1% 2C2% 2C3-tribromo-5- (trans-4- (2- (trans-4-propylcyclohexyl) ethyl) cyclohexyl) benzene, this product is on the market, and its price range is quite difficult to determine. Its price is easily influenced by many factors, such as the difficulty of preparation, the state of market supply and demand, and the quality.
If the production process is complicated, special raw materials and delicate steps are required, and time-consuming and laborious, its price will be high. Suppose the market demand for this product is strong, but the supply is scarce, and the price also tends to rise; conversely, if the demand is weak and the supply is abundant, the price may drop. Furthermore, those with high quality are often higher than those with poor quality.
Looking at the current market situation, there is no exact data to determine the exact price. However, roughly speaking, if the quality of such fine chemicals is average and the quantity is not huge, the price per gram may be between tens and hundreds of currency units; if the quality is excellent and used for high-end scientific research and special industrial purposes, the price per gram may exceed hundreds of currency units, or even higher. It should be noted that the market is unpredictable and the price fluctuates accordingly. If you want to know the accurate price, please consult the industry suppliers or market survey agencies.