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1,2,3-Trifluoro-5-Nitrobenzene

1,2,3-Trifluoro-5-Nitrobenzene

Hongda Chemical

Specifications

HS Code

680249

Chemical Formula C6H2F3NO2
Molar Mass 191.08 g/mol
Appearance Colorless to pale yellow liquid
Boiling Point 184 - 186 °C
Melting Point 14 - 16 °C
Density 1.54 g/cm³
Vapor Pressure Low at room temperature
Solubility In Water Insoluble
Solubility In Organic Solvents Soluble in common organic solvents
Flash Point 76 °C
Stability Stable under normal conditions

As an accredited 1,2,3-Trifluoro-5-Nitrobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 100g of 1,2,3 - trifluoro - 5 - nitrobenzene packaged in a sealed glass bottle.
Storage 1,2,3 - Trifluoro - 5 - nitrobenzene should be stored in a cool, dry, well - ventilated area, away from heat sources and open flames. It should be stored in a tightly - sealed container to prevent vapor leakage. Keep it separate from oxidizing agents, reducing agents, and other reactive chemicals to avoid potential reactions. Store at ambient temperature within the recommended range.
Shipping 1,2,3 - trifluoro - 5 - nitrobenzene, a chemical, is shipped in sealed, corrosion - resistant containers. Adequate labeling indicates its hazardous nature. Shipments follow strict regulations for safe transport of such chemicals.
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1,2,3-Trifluoro-5-Nitrobenzene 1,2,3-Trifluoro-5-Nitrobenzene
General Information
Historical Development
1,2,3-Trifluoro-5-nitrobenzene is also a chemical substance. At the beginning, there were few people who studied it, and only in a remote room, a few people tried to use microdevices. At that time, the skills were not refined, and it was quite difficult to obtain, and the production was also very small.
Over the years, the wisdom of scholars has gradually opened up, and the skills have improved. In the workshop of chemical industry, the rules have become larger, the law has become better, and the production has increased. Everyone works together to study the physical properties and explore the methods, and the hope is that the production will be excellent.
Today, this product is useful in all fields, and the genus of electronics and medicine relies heavily on it. Looking at its history, from the humble to the beginning, the contribution of scholars is indispensable. Since it was rare in the past, it has been commonly used today because of the progress of science and technology and the diligence of manpower.
Product Overview
"1,2,3-Trifluoro-5-nitrobenzene, Description"
1,2,3-trifluoro-5-nitrobenzene is a key chemical in organic synthesis. Its color is light yellow and it is a liquid with a special odor. In terms of chemical structure, fluorine atoms and nitro groups are cleverly arranged on the benzene ring, giving this compound unique chemical activity.
Its preparation method often follows a specific organic reaction path. After careful regulation of reaction conditions, such as temperature and catalyst selection, the effective synthesis of this compound can be achieved.
In industrial applications, 1,2,3-trifluoro-5-nitrobenzene is often an important raw material for the preparation of special functional materials and pharmaceutical intermediates. Due to the characteristics of fluorine and nitro groups, the derived products have unique physical and chemical properties and have high application value in materials science, pharmaceutical research and development and other fields.
Physical & Chemical Properties
1,2,3-Trifluoro-5-nitrobenzene is an organic compound. It has unique physical and chemical properties. Looking at its physical properties, at room temperature, it is mostly solid, white or nearly white, if crystalline, fine. Melting point and boiling point are both characteristics. The melting point is about a specific temperature range. This temperature makes the substance change from solid to liquid, which is the key node for its physical state transformation. The boiling point is also fixed. At this temperature, it liquefies into gas, which is caused by intermolecular forces.
In terms of its chemical properties, its activity varies because of its fluorine, nitro and other functional groups. The nitro group has strong electron-absorbing properties, which decreases the electron cloud density of the benzene ring, making the electrophilic substitution reaction more difficult. However, it can also occur under specific conditions. The introduction of fluorine atoms changes its chemical activity and stability, making the compound have potential uses in organic synthesis and other fields. It can be used as a key intermediate for the synthesis of special drugs and materials, and is of great significance in the process of chemical research.
Technical Specifications & Labeling
1,2,3-Trifluoro-5-nitrobenzene, also an organic compound. Its process specifications and identification (product parameters) are the key. In terms of process specifications, the synthesis method needs to be rigorous. First take an appropriate amount of fluorine-containing reagents, nitrogeners and benzene derivatives, and control them in a suitable reactor with precise temperature, pressure and reaction time. The temperature may be between tens of degrees Celsius and hundreds of degrees Celsius, and the pressure is maintained at normal pressure or slightly pressurized. The product can only be obtained when the reaction has gone through several times.
In terms of identification, the product parameters must be clear. The appearance should be a colorless to light yellow liquid or crystal with a specific melting point and boiling point. The melting point is about [X] ° C, and the boiling point is about [X] ° C. The purity must be above [X]%, and the impurity content is extremely low. In this way, the quality of 1,2,3-trifluoro-5-nitrobenzene must be ensured, so that it can be used in chemical, pharmaceutical and other fields.
Preparation Method
The preparation method of 1,2,3-trifluoro-5-nitrobenzene is related to the raw materials and production process, reaction steps and catalytic mechanism. The raw materials are often fluorobenzene and nitrogenation reagents. The fluorobenzene is used as the starting point and reacts with the nitrogenation reagent under specific conditions.
Initially, the fluorobenzene is placed in the reactor and an appropriate amount of catalyst is added to create a suitable temperature and pressure environment. Subsequently, the nitrogenation reagent is slowly injected. This process requires strict control of the rate to prevent overreaction. During the reaction, the catalyst promotes the effective introduction of nitro groups into the benzene ring and accurately localizes the 1,2,3-trifluoro-5-position.
After the reaction is complete, the product is purified through a series of post-processing processes, such as extraction, distillation, etc. The key to this preparation method is the purity of raw materials, the precise regulation of reaction conditions and the effective use of catalytic mechanisms, so as to obtain high-purity 1,2,3-trifluoro-5-nitrobenzene.
Chemical Reactions & Modifications
Since modern times, the art of chemistry has become more and more refined in the study of various compounds. In this case, the chemical reaction and modification of 1, 2, 3 - Trifluoro - 5 - Nitrobenzene are worthy of in-depth study.
Looking at its structure, the position of fluorine and nitro groups affects the reaction path. Fluorine has strong electronegativity, which changes the electron cloud density of the benzene ring, making it difficult to cause electrophilic substitution, and nucleophilic substitution is easy. Nitro also has electron absorption, and the superposition of the two is more unique.
In the reaction, the nucleophilic reagents attack it, and due to the absorption of fluorine and nitro groups, the reaction activity increases, and various products can be produced. When modifying, other groups are either introduced or substitution orders are taken to meet various needs. After ingeniously designing the reaction, new compounds with specific properties can be obtained, which are of great use in the fields of medicine and materials. The study of chemical reactions and modifications of this substance can contribute to the advancement of science and industry, and lead to new paths.
Synonyms & Product Names
The same name of 1,2,3-trifluoro-5-nitrobenzene and the name of the trade name
The name of the chemical substance, with the same name and the trade name, are all related to the characteristics and applications of the substance. Now, 1,2,3-trifluoro-5-nitrobenzene, this is its scientific name, which accurately expresses its chemical structure.
In the world, there are also all kinds of same names and trade names. Those with the same name, either because of their chemical similarities, or because of their common structure, have similar names. This is the convenience of academic exchange, so that the public can understand its genus. Trade names vary depending on the marketing and use of merchants.
1,2,3-trifluoro-5-nitrobenzene, in the field of chemical industry, either as a raw material or as an intermediate. In order to recognize its characteristics or facilitate sales, merchants take another trade name. This trade name either emphasizes its high purity or highlights its wide application. And the same name also helps researchers to quickly find related things in the vast chemical substances and explore their mysteries together. Therefore, although the same name and trade name are different from scientific names, they are of great significance in the development and application of chemistry.
Safety & Operational Standards
For 1,2,3-trifluoro-5-nitrobenzene, it is also a chemical substance. In our field of chemical research, it is essential to understand its safety and operating standards.
This substance has considerable chemical activity. Its strong nature, heat or open flame, easy to cause danger, so when storing, it must be placed in a cool and ventilated place, away from fire and heat sources to avoid accidents. The storage temperature should not exceed 30 ° C, and should be separated from oxidants and food chemicals, and should not be mixed.
When operating, all kinds of protection should not be ignored. Operators must undergo professional training and strictly abide by the operating procedures. Wear appropriate protective clothing, protective gloves and safety glasses to prevent contact with the body. If working in a poorly ventilated area, prepare effective ventilation equipment to expel harmful gases and keep the air fresh.
When using, there are also important rules. Use the amount accurately, avoid waste, and prevent excessive risk. After operation, clean the equipment used carefully to remove residues. If you accidentally come into contact with the skin, rinse quickly with a large amount of flowing water and seek medical treatment. If it enters the eye, immediately lift the eyelids, rinse with flowing water or normal saline, and seek medical attention immediately.
In case of fire, do not panic. Because it is an organic compound, it can be extinguished with dry powder and carbon dioxide fire extinguishers. Do not extinguish the fire with water to prevent the spread of the fire.
In general, the safety and operating standards of 1,2,3-trifluoro-5-nitrobenzene are related to our safety and the smooth operation of the experiment. When engraved in our hearts and followed at all times, we will be safe.
Application Area
1,2,3-Trifluoro-5-nitrobenzene is also a chemical substance. Its application area has been explored. In the field of research and development, this compound may be an important raw material. With its special properties, it may be able to be used for the synthesis of polymers, helping to produce good products and solving human suffering.
It is also useful in the field of research and development, and may also have its own uses. With its chemical properties, it may be possible to obtain high-efficiency products, protect crops from damage and ensure food production.
Furthermore, in the field of materials science, 1,2,3-trifluoro-5-nitrobenzene may be able to be used for the research of new materials. It is ingenious, or it can make the material have special properties, and it can be used for high-precision scenery. Where this is the case, it is all due to the strength of the multi-application field, which is what researchers are studying.
Research & Development
Since modern times, the art of chemistry has become more and more new, and various compounds have emerged in an endless stream. Today, there is 1, 2, 3 - Trifluoro - 5 - Nitrobenzene, which has gradually become important in our chemical research.
Our generation of scientific researchers have initially observed its properties, explored its molecular structure, and known its fluorine, nitro and other groups. After repeated experiments, observe its reaction under different conditions, or combine with other substances, or decompose itself, and record its changes in detail to clarify its chemical properties.
Then seek its application. In the field of materials, we use it as a foundation to make special materials with unique properties, such as corrosion resistance and insulation. In the field of medicine, we consider its structure to develop new drugs, hoping to cure various diseases.
However, the way of research is not smooth. The method of synthesis requires excellence, and strives for efficiency and purity. Application and promotion also face many problems, such as cost control and safety.
We should uphold the heart of research and unremitting exploration, hoping to make achievements in the research and development of 1, 2, 3 - Trifluoro - 5 - Nitrobenzene, and contribute to the progress of chemistry.
Toxicity Research
The industry of chemical industry is related to people's livelihood, but the study of poisons is also an important matter. Now on 1, 2, 3 - Trifluoro - 5 - Nitrobenzene, the study of its toxicity should not be ignored.
Look at this substance, its strong nature, with signs of toxicity. In various experiments, observe its effect on living beings, it can be seen that the micro-dose can also cause changes in the body. Small animals touch it, or they may be in violation of their physiology, their actions are sluggish, and even their lives are endangered. Its poison enters the body, follows the blood vessels and meridians, disturbs the normal organs, and disrupts the order of qi and blood.
Investigate the reason for its toxicity, including its unique molecular structure, which breaks the balance of cells and blocks the way of metabolism between biochemical reactions. Although its use may be beneficial, toxicity cannot be prevented. Researchers should be in awe, exercise the rules of the experiment, observe its nature carefully, avoid disasters for the world, and ensure the safety of the chemical industry.
Future Prospects
1, 2, 3 - Trifluoro - 5 - Nitrobenzene, it is also a matter of transformation. Now we can explore the prospects of its future, and the capabilities of its limitations. In the field of development, it may be the foundation for making new special effects, helping those who solve diseases and save their lives from pain. In the realm of materials, it may be able to improve the characteristics of new materials, making utensils more efficient, and use them in high-tech utensils. Furthermore, in the field of production, or in the research of high-efficiency damage, protection of crops, and protection of crops. The road ahead may be exciting, but our researchers must work hard to understand and explore them, hoping that this material can be used in the future and benefit the world.
Where to Buy 1,2,3-Trifluoro-5-Nitrobenzene in China?
As a trusted 1,2,3-Trifluoro-5-Nitrobenzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
Frequently Asked Questions

As a leading 1,2,3-Trifluoro-5-Nitrobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the main uses of 1,2,3-trifluoro-5-nitrobenzene?
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, the road to medicine. This compound is quite useful in the field of pharmaceutical research and development. Its unique structure can act on specific targets in the human body. After many studies, it may be helpful for the treatment of certain diseases. For example, in the process of resisting diseases, it can regulate biochemical reactions in the body, or enhance the immune function of the human body, so as to achieve the purpose of curing diseases and protecting health.
Both, the road of scientific research. As an important object of chemical research, it can contribute to the development of organic chemistry. It can help researchers understand the relationship between the structure and characteristics of organic molecules, and can also provide ideas and examples for the synthesis of new compounds. Through the study of its reaction characteristics, novel synthesis paths can be developed, the boundaries of chemical synthesis can be expanded, and the progress of chemical disciplines can be promoted.
The three are used in industrial production. In the fine chemical industry, it may serve as an important raw material or intermediate. With its unique chemical properties, it can be converted into various high-value-added products through a series of processes, such as materials with special properties, fine chemicals, etc., thereby promoting the innovation of industrial production and improving industrial economic benefits.
From this perspective, 1%2C2%2C3-%E4%B8%89%E6%B0%9F-5-%E7%A1%9D%E5%9F%BA%E8%8B%AF%E7%9A%84 has a wide range of uses and cannot be ignored in many fields such as medicine, scientific research, and industry.
What are the physical properties of 1,2,3-trifluoro-5-nitrobenzene?
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This substance has unique properties. Its state is usually solid, and the quality is relatively stable. However, under specific temperature and pressure conditions, it may have a different form.
In terms of its melting point, after testing, it is within a certain range. However, it may vary slightly due to the surrounding environment. Its boiling point is also fixed. When the temperature rises to a corresponding level, it changes from liquid to gaseous.
Its density is also one of its characteristics. Compared with other substances, it can be distinguished according to this. In terms of solubility, it may be soluble or insoluble in some common solvents, such as water, depending on specific chemical principles and conditions. Or in organic solvents, it exhibits unique solubility properties, which are all related to molecular structure and interactions.
In terms of conductivity, due to the movement characteristics of electrons in the internal structure, it is either a good conductor, an insulator, or a semiconductor, which is related to whether electrons can move smoothly in the lattice. Thermal conductivity is also expressed. If the internal atomic or molecular vibration is effective in transferring heat energy, the thermal conductivity is excellent, and vice versa.
These physical properties are important in many fields. In chemical production, it is related to the synthesis and separation process; in material science, it is the basis for the development of new materials and the optimization of performance; in the field of medicine, or affects the transfer and absorption of drugs, etc., which is an indispensable consideration.
Is the chemical property of 1,2,3-trifluoro-5-nitrobenzene stable?
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The chemical properties of this substance are quite stable in common sense. Looking at the structure of this compound, 1%2C2%2C3-%E4%B8%89%E6%B0%9F part, its carbon chain structure is relatively regular, and the connected 5-%E7%A1%9D%E5%9F%BA%E8%8B%AF, so that the intermolecular forces are adjusted.
Whether it is stable or not depends on the environment. Under normal temperature and pressure, without special reagents or strong external conditions, its chemical bonds can maintain a predetermined state, and its chemical properties are stable. In case of high temperature, the thermal motion of molecules intensifies, and the chemical bonds may break, causing chemical changes. In addition, in case of strong oxidizing agents or strong reducing agents, because of their structure or reactive activity check points, they may also trigger chemical reactions, thereby changing their chemical properties. If
is placed in an acid-base environment, there may be groups in the structure of the substance that can interact with acid and base, or will participate in acid-base reactions, which will affect its stability. However, in general, if there is no interference from the above special external conditions, this 1%2C2%2C3-%E4%B8%89%E6%B0%9F-5-%E7%A1%9D%E5%9F%BA%E8%8B%AF is stable in common environments.
What are the preparation methods of 1,2,3-trifluoro-5-nitrobenzene?
1% 2C2% 2C3-tribromo-5-nitrobenzene is an important compound in organic synthesis. Its preparation method has been studied by predecessors, and several common methods are described below.
One is the method using benzene as the starting material. First, the benzene is nitrified, and the mixed acid of concentrated nitric acid and concentrated sulfuric acid is used as a reagent. At a suitable temperature, nitrobenzene can be obtained. After the nitrobenzene is brominated under specific conditions, the bromine atom is gradually introduced with liquid bromine as the bromine source and iron tribromide as the catalyst, and 1% 2C2% 2C3-tribromo-5-nitrobenzene can be obtained. The steps of this pathway are relatively clear, but the reaction conditions of each step need to be precisely controlled, otherwise side reactions will easily occur, which will affect the purity and yield of the product.
The second can be started from other aromatic compounds. If an aromatic hydrocarbon containing a specific substituent is used as the starting material, the target product can also be obtained by ingenious functional group conversion and substitution reactions. First, nitro groups are introduced by electrophilic substitution reaction, and then the position and type of substituents are adjusted by appropriate reactions, and then bromine atoms are introduced. This way requires a deep understanding of various organic reaction mechanisms and ingenious design of reaction routes to achieve the purpose of efficient synthesis.
The third is to use some special synthesis strategies. Such as reactions catalyzed by transition metals, cross-coupling reactions catalyzed by palladium, etc. With a suitable substrate containing bromine and nitro group, the target molecular structure is constructed by coupling and other steps under the action of palladium catalyst and ligand. Such methods often have the advantages of mild reaction conditions and high selectivity. However, the cost of the catalyst is higher, and the requirements for the reaction equipment and operation are also higher.
Preparation of 1% 2C2% 2C3-tribromo-5-nitrobenzene is diverse, with advantages and disadvantages. Experimenters should choose suitable methods and carefully optimize the reaction conditions according to their own conditions, such as raw material availability, equipment status, cost considerations, etc., to obtain satisfactory results.
What are the precautions for storing and transporting 1,2,3-trifluoro-5-nitrobenzene?
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This medicine is special and sensitive, and it is easy to change its properties when exposed to light, heat, and humidity. Therefore, it must be hidden in a cool, dry, and dark place, and the temperature should be controlled between 15 and 25 degrees Celsius. If it is too cold or too hot, it will damage its effectiveness. The container should also be carefully selected, and it is better to use glass or specific plastic devices, because it can resist the disturbance of external factors and ensure the stability of the medicine.
When transported, shock resistance and collision prevention are the top priorities. This medicine is delicate in quality. If it is shocked or hit violently, its internal molecular structure is easy to be messed up, and its efficacy is also harmed. Those who carry it must handle it with care and take extra care. And the transportation should also be the same as Tibet, so that the temperature and humidity are suitable, and the light does not enter.
Also, the clarity of the label is very important. The hiding place and the transportation equipment should be clearly signed, and the name of the book and medicine, sex, use, Tibetan method, and pay attention to all things, so that people can see at a glance, and there is no mistake. Everyone should abide by this rule to ensure 1%2C2%2C3-%E4%B8%89%E6%B0%9F-5-%E7%A1%9D%E5%9F%BA%E8%8B%AF%E5%9C%A8%E5%82%A8%E5%AD%98%E8%BF%90%E8%BE%93%E4%B8%AD%E7%9A%84%E5%AE%89%E5%85%A8%E4%B8%8E%E6%95%88%E7%8E%87%EF%BC%8C%E4%BB%A5%E5%88%A9%E7%96%97%E8%80%85%E7%94%A8%E4%B9%8B%E3%80%82