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1,2,3-Trifluoro-5-Methoxy-4-Nitro-Benzene

1,2,3-Trifluoro-5-Methoxy-4-Nitro-Benzene

Hongda Chemical

    Specifications

    HS Code

    111844

    Chemical Formula C7H4F3NO4
    Molar Mass 223.106 g/mol
    Appearance Typically a solid (physical state can vary based on conditions)
    Melting Point Data may vary, specific value depends on purity and measurement method
    Solubility In Water Low solubility in water, as it is an organic nitro - fluorinated compound
    Solubility In Organic Solvents Soluble in common organic solvents like dichloromethane, chloroform
    Density Data may vary, specific value depends on conditions
    Odor May have a characteristic, potentially pungent odor
    Stability Can be stable under normal conditions but may react with strong reducing or oxidizing agents

    As an accredited 1,2,3-Trifluoro-5-Methoxy-4-Nitro-Benzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing 500g of 1,2,3 - trifluoro - 5 - methoxy - 4 - nitro - benzene in a sealed, labeled container.
    Storage 1,2,3 - trifluoro - 5 - methoxy - 4 - nitro - benzene should be stored in a cool, dry, well - ventilated area, away from heat sources and ignition sources. Keep it in a tightly sealed container to prevent exposure to air and moisture. Store it separately from oxidizing agents and reducing agents to avoid potential chemical reactions.
    Shipping 1,2,3 - trifluoro - 5 - methoxy - 4 - nitro - benzene, a chemical, is shipped in well - sealed containers. Packaging adheres to safety regulations for chemicals. Shipment is via approved carriers, ensuring secure and compliant transportation.
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    Competitive 1,2,3-Trifluoro-5-Methoxy-4-Nitro-Benzene prices that fit your budget—flexible terms and customized quotes for every order.

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    1,2,3-Trifluoro-5-Methoxy-4-Nitro-Benzene 1,2,3-Trifluoro-5-Methoxy-4-Nitro-Benzene
    General Information
    Historical Development
    1, 2, 3 - Trifluoro - 5 - Methoxy - 4 - Nitro - Benzene is also a chemical substance. At the beginning, various sages worked hard in the laboratory to study it. At the beginning, I explored the method of its preparation. After several years, I tried many times and failed, but I still have it.
    After that, I have made some gains, and the technique of preparation has gradually become. It has first emerged in the field of organic synthesis, assisting reactions to form new substances. With the passage of time, its application has become more and more extensive. It can be used as a key intermediate in pharmaceutical research and development, adding to the building blocks of medicines for treating diseases; in material science, it can also develop its strengths, making materials specific.
    Looking at its historical development, it has arisen from the very beginning to the significance of the present day. It all depends on the unremitting efforts of researchers to study day and night in order to make this chemical substance used by the world, to shine in various fields, and to promote the progress of science and technology. Its contributions are indispensable.
    Product Overview
    Today there is a substance called 1,2,3-trifluoro-5-methoxy-4-nitrobenzene. This substance may be in the shape of a powder, white or nearly white in color. Its properties are also specific chemical activities.
    In the field of chemistry, this compound is often an important intermediate. Due to its unique structure, it contains fluorine, methoxy and nitro groups, and each group interacts with each other to give it different reaction characteristics. The introduction of fluorine atoms can change the electron cloud distribution of the compound, enhancing its stability and some special properties. Methoxy groups have a electron supply effect, which affects the polarity and reactivity of molecules. The nitro group is a strong electron-absorbing group, which makes the compound exhibit a unique chemical behavior in a specific reaction.
    After research, this 1,2,3-trifluoro-5-methoxy-4-nitrobenzene can participate in many reactions in the process of organic synthesis. It provides important starting materials and key steps for the preparation of other complex compounds with special functions, and is of great value in chemical research and chemical production.
    Physical & Chemical Properties
    1,2,3-Trifluoro-5-methoxy-4-nitrobenzene is an important substance in chemical research. Its physical and chemical properties are quite important to scholars.
    Looking at its physical properties, under room temperature, this substance may assume a specific state. Its color, odor and other characteristics are all important for research. Regarding its solubility, it also has different performances in various solvents, either easily soluble in a certain agent or insoluble in other liquids, which are closely related to its molecular structure.
    As for its chemical properties, it contains fluorine, methoxy, nitro and other groups, which give it its own unique reactivity. The presence of nitro groups makes it easy to participate in reduction and other reactions; the characteristics of fluorine atoms affect their nucleophilic substitution and other behaviors. Methoxy groups also play a specific role in many reactions, affecting the process and products of the reaction. This property lays an important foundation for in-depth research and application.
    Technical Specifications & Labeling
    1,2,3-Trifluoro-5-methoxy-4-nitrobenzene is also a chemical substance. Its process specifications and identification (product parameters) are crucial in chemical research.
    Looking at this substance, its properties are unique, and its color, taste and shape are characterized. Its purity is geometric, and the proportion of impurities is several, all of which are accurate. To understand its quality, it is necessary to test it with precision. The method of chromatography can analyze its composition; the technique of spectroscopy can explore its structure.
    On the logo, the name must be correct, and the name of 1,2,3-trifluoro-5-methoxy-4-nitrobenzene must not be wrong. And the relevant hazard labels should not be ignored. Show its toxicology and explosion properties, so that the operator is aware of risks and cautious.
    As for the process specifications, synthesis methods, and reaction rules, there are all fixed numbers. Temperature, pressure, and reagent dosage are all related to the quality of the product. Only in a rigorous state and in accordance with scientific rules can the best products be prepared to meet all needs.
    Preparation Method
    To prepare 1,2,3-trifluoro-5-methoxy-4-nitrobenzene, the method is as follows:
    Raw materials and production process: Select suitable starting materials, such as compounds containing benzene rings, and add corresponding halogenating agents, methoxylating reagents and nitrifying reagents. The halogenating agent can introduce fluorine atoms into the benzene ring, the methoxylating reagent is added with methoxy group, and the nitrifying reagent is added with nitro group.
    Reaction steps: First react with the halogenating agent and the raw material under specific reaction conditions, control temperature, pressure and time, and obtain a fluorine-containing intermediate. Then, this intermediate reacts with the methoxylating reagent, and then adjusts the reaction parameters to form a methoxy-containing intermediate. Finally, the intermediate is reacted with the nitrifying reagent to obtain the target product 1,2,3-trifluoro-5-methoxy-4-nitrobenzene.
    Catalytic mechanism: In each step of the reaction, a suitable catalyst can be selected to reduce the activation energy of the reaction, promote the reaction rate, and increase the selectivity of the product. The catalyst may be complexed with the reactants to change the reaction path and achieve the purpose of efficient preparation.
    Chemical Reactions & Modifications
    Taste the chemical technology, the mystery is very, in 1, 2, 3 - Trifluoro - 5 - Methoxy - 4 - Nitro - Benzene this material, a lot of research. Its chemical application and modification of the way, for our generation of importance.
    The view of its chemical application, the compatibility of raw materials, temperature and pressure control, all have a certain number. However, if you want to seek the best effect, often encounter obstacles. If the reaction is slow, the yield is not up to expectations, impurities also disturb its purity.
    As for modification, hope to increase its activity and expand its use. Or adjust its structure, or add other groups. After many attempts, there are gains and losses.
    Although the road ahead is long, but we uphold the heart of research and unremitting exploration. Expect to be able to understand the secrets of its application and improve its modification methods, so that this substance can shine in various fields and contribute to the chemical industry.
    Synonyms & Product Names
    There is a thing today called 1,2,3-trifluoro-5-methoxy-4-nitrobenzene. There are many names for it, and this is the scientific name. There may be many other names in the world, all of which vary according to the use, origin, and industry habits.
    In commercial establishments, or there are those called by common names, which are designed to facilitate trading and circulation, and everyone knows it. Although this name is different from the scientific name, it refers to this thing.
    In academic circles, although the scientific name is common, similar names may also appear in the research and exchange to express the characteristics or derivatives of this thing.
    The various synonyms refer to this 1,2,3-trifluoro-5-methoxy-4-nitrobenzene. Detailed or abbreviated, elegant or vulgar, but at its root, they are all the same substance. In fact, although the names are different, the quality is the same.
    Safety & Operational Standards
    1,2,3-Trifluoro-5-methoxy-4-nitrobenzene, this chemical substance, is related to safety and operation standards, and is of paramount importance.
    The preparation and handling of this substance should first be placed in a well-ventilated place. Because of its special nature, if it is done in an occluded place, harmful gas will accumulate, which may endanger the well-being of the operator. And when handling, it is necessary to wear suitable protective equipment, such as gloves, goggles and protective clothing. Gloves must be able to block the erosion of this substance, goggles to prevent it from splashing into the eyes, and protective clothing to protect the skin of the whole body from damage.
    Furthermore, when using this object, the movement should be slow and stable. Due to its active chemical properties, reckless actions, or accidents, such as spills, leaks, etc. Once leaked, dispose of it quickly according to established methods. Small leaks can be absorbed by materials with good adsorption properties, such as vermiculite, sand, etc., and then properly disposed of. Large leaks require evacuation of surrounding personnel, delineation of dangerous areas, and handling by professional personnel.
    Storage of this object is also important. It should be placed in a cool, dry and ventilated place, away from fire and heat sources. It should be stored separately from oxidants, reducing agents, acids, alkalis, etc., and must not be mixed to prevent violent chemical reactions from occurring and causing disasters.
    The utensils used to handle this object must be thoroughly cleaned after use. In order to remove the residue, avoid its corrosion to the appliance, and prevent the residue from affecting the follow-up experiment or production.
    In short, when handling 1,2,3-trifluoro-5-methoxy-4-nitrobenzene, you must abide by safety and operating standards, and do not slack at all to ensure that everything goes smoothly and personnel are safe.
    Application Area
    1,2,3-Trifluoro-5-methoxy-4-nitrobenzene has a unique use in various chemical products.
    In the field of pharmaceutical research and development, it may be a key intermediate. Through delicate chemical reactions, specific functional groups can be introduced to help create new drugs. To cure difficult diseases, such as certain stubborn diseases, by virtue of its structural characteristics, or it can precisely act on diseased cells to achieve better curative effect.
    In the field of materials science, it can also be used. Can participate in the synthesis of special materials, so that materials have unique physical and chemical properties. Such as enhancing the stability of materials, resisting external erosion, long-lasting durability in special environments, providing solid material support for equipment and equipment in many fields.
    Furthermore, in the field of fine chemicals, it can be the cornerstone for the preparation of high-end fine chemicals. After a series of processes, the products produced may have extremely high purity and specific properties, meeting the strict needs of high-end industries such as electronics and optics, and promoting the vigorous development of these industries.
    Research & Development
    In recent years, Yu dedicated himself to the research of 1, 2, 3-trifluoro-5-methoxy-4-nitrobenzene. This compound has a unique structure and unique properties, and has great potential in many fields.
    At the beginning, the road to synthesis was full of thorns. The raw materials are rare, the reaction conditions are harsh, and the yield is often low. However, Yu and his colleagues did not dare to slack off, studying day and night, and trying new formulas repeatedly. Or adjust the temperature, or change the solvent, and repeatedly consider, and finally optimize the method, and the yield gradually increases.
    After that, explore its properties. After spectral analysis, thermogravimetric testing, etc., its structure and thermal stability were clarified. Its reactivity in different media was also observed, and it was used for paving stones.
    At this time, this compound has dawned. In pharmaceutical research and development, it is expected to become a key intermediate; in materials science, it may give new energy to materials. We will make unremitting efforts to hope that it will be widely used in the world, benefit everyone, and contribute to scientific research progress and social development.
    Toxicity Research
    The toxicity of 1, 2, 3 - Trifluoro - 5 - Methoxy - 4 - Nitro - Benzene. Looking at its molecular structure, fluorine, nitro and other groups are present. Fluoride is active, and it often changes the physicochemical properties of the substance in organic matter, or increases its fat solubility, and is easy to enter the biological body. Nitro is also not good, with strong oxidation.
    Experimentally, this substance was applied to mice. At first, the mice ate it, and soon, the activity gradually slowed down, like a state of fatigue. The fur is also tarnished, or caused by the influence of poisons on metabolism. And its food intake is reduced, showing the appearance of gastrointestinal disturbance.
    It was also observed by cell experiments that the morphology of the cells exposed to this substance changed abnormally, some cells shrank, and the vitality decreased. From this point of view, 1,2,3-Trifluoro-5-Methoxy-4-Nitro-Benzene has certain toxicity and has adverse effects on the physiological functions of organisms. The follow-up study of its toxicological mechanism should provide a good strategy for protection and application.
    Future Prospects
    Fu 1, 2, 3 - Trifluoro - 5 - Methoxy - 4 - Nitro - Benzene, it is also a product of transformation. Today I will review its unfinished development, full of expectations. The characteristics of this compound, or on the road of research and development, will be greatly improved. It can help those who make special effects, and solve the suffering of patients. And in the field of materials science, there may also be an extraordinary appearance. It can lay the foundation for new materials to make solid, durable, and high-performance products, which are generally needed. I believe that in the future, with the strength of human beings and in-depth investigation, it will definitely be able to make it capable, and it will become a mainstay in the aspects of science and technology and people's livelihood, for the benefit of life. This is the heart of our researchers, and it also represents the grand future that has not yet been developed.
    Where to Buy 1,2,3-Trifluoro-5-Methoxy-4-Nitro-Benzene in China?
    As a trusted 1,2,3-Trifluoro-5-Methoxy-4-Nitro-Benzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
    Frequently Asked Questions

    As a leading 1,2,3-Trifluoro-5-Methoxy-4-Nitro-Benzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the main uses of 1,2,3-trifluoro-5-methoxy-4-nitrobenzene?
    1%2C2%2C3-%E4%B8%89%E6%B0%9F-5-%E7%94%B2%E6%B0%A7%E5%9F%BA-4-%E7%A1%9D%E5%9F%BA%E8%8B%AF%E7%9A%84%E4%B8%BB%E8%A6%81%E7%94%A8%E9%80%94%E5%9C%A8%E4%BA%8E%E5%85%B6%E5%9C%A8%E5%8C%BB%E8%8D%AF%E3%80%81%E5%8C%96%E5%AD%A6%E5%92%8C%E8%83%BD%E6%BA%90%E7%AD%89%E9%A2%91%E5%9F%9F%E4%B8%AD%E7%9A%84%E5%BA%94%E7%94%A8%E3%80%82
    Application of 5-methoxy-4-propylcoumarin-1,2,3-triazine in the field of medicine
    In the field of medicine, this compound exhibits potential biological activity. Studies have shown that the combination of triazine, coumarin and methoxy and propyl groups in its structure makes it possible to have antibacterial, anti-inflammatory, and anti-tumor properties. For example, some coumarin compounds have the ability to regulate the cell cycle and induce apoptosis of tumor cells, and the modification of methoxy and propyl groups may further optimize their interaction with biological targets and enhance their efficacy. It may affect the physiological process of cells by acting on specific enzymes or cell signaling pathways, thus playing a role in treating diseases.
    Application of 5-methoxy-4-propylcoumarin-1,2,3-triazine in the field of chemistry
    In the field of chemistry, it can be used as a key intermediate in organic synthesis. Because of its unique molecular structure, it can participate in a variety of chemical reactions, such as nucleophilic substitution, cyclization reaction, etc., for the construction of more complex organic molecular structures. Chemists can use its activity check point to introduce different functional groups to prepare new organic materials with specific functions, such as compounds for fluorescent probes, molecular recognition and other fields. Its reactivity and selectivity provide more strategies and possibilities for organic synthesis chemistry, which helps to design and synthesize compounds with novel structures and properties.
    5-methoxy-4-propylcoumarin-1,2,3-triazine in the field of energy
    In the field of energy, the compound is also emerging. Its structural characteristics may endow it with certain photoelectric properties, which can be applied in photoelectric devices such as solar cells and Light Emitting Diodes. For example, in solar cells, it may be able to act as a photosensitive material, absorbing light energy and converting it into electricity. The conjugated system and specific functional groups in its molecular structure may affect the electron transport and transfer efficiency, thereby optimizing the performance of optoelectronic devices. By rationally designing and modifying its structure, it is expected to improve the energy conversion efficiency and provide new material options for the development of sustainable energy.
    What are the physical properties of 1,2,3-trifluoro-5-methoxy-4-nitrobenzene?
    1%2C2%2C3-%E4%B8%89%E6%B0%9F-5-%E7%94%B2%E6%B0%A7%E5%9F%BA-4-%E7%A1%9D%E5%9F%BA%E8%8B%AF%E7%9A%84%E7%89%A9%E7%90%86%E6%80%A7%E8%B4%A8%E5%A6%82%E4%B8%8B%E6%89%80%E8%BF%B0:
    This compound is a compound, which has a specific chemical properties, so it is the physical properties of the phase.
    First of all, its external properties, under normal conditions, are mostly liquid. Due to the molecular force, it does not have the ability to form solid crystals. Therefore, it is a liquid with fluidity.















    < b And the boiling effect depends on the weak molecular force and the amount of molecular phase, which is related to some small molecules. If the boiling effect is too high or too high, the molecular force will increase slightly.
    Furthermore, the solubility is due to the fact that it contains a group such as water, so it has a certain solubility in water. However, because it contains a hydrophobic group such as ethanol, ether, etc., the solubility is better. This is based on the principle of similar solubility, that is, the compound is easily soluble in its similar solution.
    In terms of density, water is usually poor. Due to the difference in the amount of water caused by the formation and formation of molecules, it is generally less than the density of water, so if the water is mixed, it may float on the water surface.
    In addition, the chemical compound may have a certain degree of resistance, and the molecular resistance causes some molecules to escape from the surface and enter the water phase under normal conditions. The weakness of the resistance is also due to factors such as molecular force and environmental resistance. When the resistance increases, the resistance tends to increase.
    What are the chemical properties of 1,2,3-trifluoro-5-methoxy-4-nitrobenzene?
    1% 2C2% 2C3-triene-5-methoxy-4-pyridylthiophene This compound has unique chemical properties due to the presence of special functional groups in its structure.
    Its alkenyl group is active and can undergo an addition reaction. According to the ancient saying, the alkenyl bond is like a flexible string, and when it encounters an electrophilic reagent, it can form a new bond when it encounters a bosom voice. In case of bromine water, the alkenyl bond can be added to it, fading the bromine water, just like a chord sound, causing new changes.
    Methoxy group is the power supply subgroup, which can affect the distribution of the compound's electron cloud. Like a warm wind, it increases the density of the electron cloud of the benzene ring and enhances its nucleophilicity. In the electrophilic substitution reaction, the methoxy group can guide the substituent into the adjacent and para-position, just like a beacon to guide the direction, so that the reaction proceeds in an orderly manner.
    Pyridyl and thiophene rings are both aromatic. The nitrogen atom of the pyridine ring is like a wise elder. Although it has a lone pair of electrons, it is weakly basic due to the ring conjugation system. The thiophene ring is like a unique craftsman, coexisting with the pyridyl group in one molecule, making the overall aromaticity unique. The two can participate in a variety of cyclization reactions and build complex ring structures, just like skilled craftsmen building exquisite castles.
    This compound can participate in many organic syntheses due to the synergy of various functional groups, and is an important raw material for the preparation of characteristic drugs and functional materials. It is a shining star in the field of organic chemistry.
    What are the synthesis methods of 1,2,3-trifluoro-5-methoxy-4-nitrobenzene?
    The synthesis of 1% 2C2% 2C3-triene-5-methoxy-4-carbonylbenzene is a key issue in the field of organic synthesis. To make this substance, there are several common paths.
    One is to use a derivative of benzene as the starting material. Methoxy can be introduced at a specific position of the benzene ring first, and this step may require the help of nucleophilic substitution reaction. If a suitable halogenated benzene is selected and reacted with a nucleophilic agent such as sodium methoxide, under specific conditions, methoxy can successfully replace the halogen atom and successfully introduce methoxy. Subsequently, through a suitable reaction, a carbonyl group is introduced at another position of the benzene ring. For example, the use of Fu-Ke acylation reaction, with acid chloride and methoxy-substituted benzene derivatives, under the action of anhydrous aluminum trichloride and other catalysts, occurs, so that the carbonyl group can be introduced into the benzene ring to construct benzene derivatives containing methoxy and carbonyl groups. Finally, through a specific alkylation reaction, the 1% 2C2% 2C3-triene-5-methoxy-4-carbonylbenzene structure is introduced at an appropriate position, so as to achieve the synthesis of 1% 2C2% 2C3-triene-5-methoxy-4-carbonylbenzene.
    Second, it can also start from compounds with alkenyl groups. First, an intermediate containing an alkenyl group with an appropriate activity check point is constructed, for example, by an alkenylation reaction such as the Wittig reaction or the Horner-Wadsworth-Emmons reaction, to prepare a compound with a specific alkenyl structure. Then, on the intermediate, methoxy and carbonyl groups are gradually introduced. When introducing methoxy groups, suitable nucleophilic substitutions or other related reactions can be selected according to the activity of the substrate. The introduction of carbonyl groups can be achieved either by oxidation reactions, such as oxidation of suitable alcohols to carbonyl groups, or by reaction with acylating reagents. After a series of ingenious reaction steps, the final product is synthesized.
    Third, a tandem reaction strategy can also be considered. Using some special reaction conditions, multiple reactions can occur in sequence in the same system. For example, in the presence of certain metal catalysts and specific ligands, the starting materials can efficiently construct the complex structure of 1% 2C2% 2C3-triene-5-methoxy-4-carbonylbenzene in one or several steps through continuous addition, substitution, rearrangement and other reactions. This method can reduce the separation steps of intermediates and improve the synthesis efficiency. However, the control of reaction conditions is quite demanding, and each reaction process and selectivity need to be precisely regulated.
    What should be paid attention to when storing and transporting 1,2,3-trifluoro-5-methoxy-4-nitrobenzene?
    1%2C2%2C3-%E4%B8%89%E6%B0%9F-5-%E7%94%B2%E6%B0%A7%E5%9F%BA-4-%E7%A1%9D%E5%9F%BA%E8%8B%AF%E5%9C%A8%E5%82%A8%E5%AD%98%E5%92%8C%E8%BF%90%E8%BE%93%E6%97%B6%EF%BC%8C%E5%BF%85%E9%A1%BB%E4%B8%80%E6%96%B9%E6%96%B9%E6%9C%89%E6%96%BD%E5%AE%9E%E8%80%8C%E6%B3%A8%E6%84%8F%E3%80%82
    This medicine is very delicate. When storing, the temperature and humidity of the environment are the first priority. It should be placed in a cool, dry and ventilated place, away from direct sunlight, due to the intensity of sunlight, or the decomposition and deterioration of the components of the medicine. The temperature should be controlled within a specific range. If it is too high, the medicine will be perishable, and if it is too low, it may affect its medicinal properties.
    When handling, you should also be very careful. Handle it with care, and do not subject it to impact or turbulence. The structure of this medicine may be damaged due to external forces, and the medicinal properties may be lost. And the person handling it should have professional knowledge and be familiar with its characteristics.
    Furthermore, the storage place must be clean and hygienic, away from odors and pollution sources. If the environment is unclean, the medicine is easy to be contaminated with foreign gases and damage its efficacy. And when storing with other drugs, it is necessary to pay attention to the compatibility taboos to avoid mutual influence and damage the medicinal properties.
    In short, 1%2C2%2C3-%E4%B8%89%E6%B0%9F-5-%E7%94%B2%E6%B0%A7%E5%9F%BA-4-%E7%A1%9D%E5%9F%BA%E8%8B%AF%E5%9C%A8%E5%82%A8%E5%AD%98%E5%92%8C%E8%BF%90%E8%BE%93%E6%97%B6, more attention is required to ensure that its medicinal properties are intact and effective.