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1,2,3,5-Tetrafluorobenzene

1,2,3,5-Tetrafluorobenzene

Hongda Chemical

Specifications

HS Code

592264

Chemical Formula C6H2F4
Molecular Weight 148.07
Appearance Colorless liquid
Boiling Point 114 - 115 °C
Melting Point -34 °C
Density 1.409 g/cm³
Solubility Insoluble in water, soluble in organic solvents
Flash Point 17 °C
Refractive Index 1.4092
Odor Typical aromatic odor

As an accredited 1,2,3,5-Tetrafluorobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 1,2,3,5 - tetrafluorobenzene in 5 - liter sealed drums for chemical packaging.
Storage 1,2,3,5 - Tetrafluorobenzene should be stored in a cool, well - ventilated area, away from heat sources and open flames. Keep it in a tightly - sealed container to prevent vapor leakage. Store it separately from oxidizing agents and reactive substances. The storage area should be dry to avoid any potential reactions with moisture.
Shipping 1,2,3,5 - Tetrafluorobenzene is shipped in tightly sealed, specialized containers compliant with chemical transport regulations. It's transported under controlled conditions to prevent spills and ensure safety during transit.
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1,2,3,5-Tetrafluorobenzene 1,2,3,5-Tetrafluorobenzene
General Information
Historical Development
1,2,3,5 - Tetrafluorobenzene is an organic compound, and its development process is very interesting. In the past, at the beginning of chemical research, the knowledge of such fluorine-containing compounds was still shallow. As the years passed, chemists continued to explore and study the methods of fluorine-containing organic synthesis.
In the early days, the synthesis technology was limited, and the preparation of 1,2,3,5 - Tetrafluorobenzene was difficult, with low yields and many impurities. However, scientists worked tirelessly to improve the reaction conditions and explore new catalysts. After countless attempts, the synthesis process has gradually improved.
Today, 1,2,3,5 - Tetrafluorobenzene has emerged in many fields such as materials science, medical chemistry, and plays a key role. Its historical evolution is a testament to the continuous progress and innovation of chemical research, and also paves the way for more fluorine-containing compound research in the future.
Product Overview
1,2,3,5 - Tetrafluorobenzene is an organic compound. Its molecule contains a benzene ring, and four hydrogen atoms on the benzene ring are replaced by fluorine atoms. This compound has unique physical and chemical properties. It is mostly liquid at room temperature, has certain volatility, and has good solubility in organic solvents.
It is widely used in the field of organic synthesis and can be used as a key intermediate for the preparation of various fluorine-containing fine chemicals. Due to the high electronegativity of fluorine atoms, the introduction of this compound can significantly change the electron cloud density and spatial structure of the compound, giving the product unique properties such as higher stability and biological activity.
Preparation of 1,2,3,5-Tetrafluorobenzene often requires multi-step reactions, involving complex organic reaction steps such as halogenation and substitution. Strict control of reaction conditions requires precise regulation of temperature, pressure and catalyst use to improve product purity and yield.
Physical & Chemical Properties
1,2,3,5 - Tetrafluorobenzene is an organic compound, and its physicochemical properties are particularly important. Looking at its physical properties, under normal temperature and pressure, it is mostly liquid, with a clear and transparent color and a slightly special odor. Its boiling point is suitable, which is conducive to operations such as distillation and separation; the melting point also has characteristics, which limit the conditions for its storage and transportation. As for the chemical properties, because it contains fluorine atoms, the electron cloud density distribution is different from that of normal substances, so the reactivity is unique. The conjugated system of benzene ring allows it to participate in many electrophilic substitution reactions. The electron-absorbing effect of fluorine atoms has a deep impact on the reaction check point and rate. This compound is widely used in the field of organic synthesis and can be a key raw material for the preparation of special functional materials and pharmaceutical intermediates. It is an important task for chemical research to explore its physical and chemical properties.
Technical Specifications & Labeling
1, 2, 3, 5 - Tetrafluorobenzene is also an organic compound. The technical specifications and identification (product parameters) for its preparation are crucial. To make this product, follow specific process regulations. First take an appropriate amount of raw materials, mix them in a precise ratio, and perform a chemical reaction under specific temperature and pressure conditions by the effect of a catalyst.
During the preparation process, the operating procedures must be strictly followed to ensure the stability of the reaction environment, precise temperature control and pressure control to improve the purity and yield of the product. In terms of identification, when specifying its chemical properties and physical parameters, such as melting point, boiling point, density, etc., warning information is also required to indicate its potential danger. In this way, we can meet the requirements of technical specifications and labels to produce high-quality 1,2,3,5-Tetrafluorobenzene products.
Preparation Method
The method of preparing 1,2,3,5-tetrafluorobenzene is related to the raw materials and production process, reaction steps and catalytic mechanism. The raw materials are often fluorinated compounds, which are formed by multi-step reaction.
First take a suitable fluorinated reagent, mix it with a benzene derivative, and initiate a substitution reaction at a specific temperature and pressure. This step requires precise temperature control to make the reaction progress steadily. During the reaction, fluorine atoms gradually replace hydrogen atoms at specific positions on the benzene ring.
The reaction steps are orderly. The substitution check point is first determined, and then the reaction is sequential to ensure that the fluorine atoms are arranged in 1, 2, 3, and 5 positions. The catalytic mechanism is also critical. High-efficiency catalysts, such as metal fluoride catalysts, are selected to accelerate the reaction process and improve product selectivity and yield. Through this series of operations, 1, 2, 3, 5-tetrafluorobenzene products can be obtained.
Chemical Reactions & Modifications
Taste the industry of chemical industry, in the change of substances, delve into the micro. Today there is 1, 2, 3, 5 - Tetrafluorobenzene, which is related to the chemical reaction and modification, and is very important.
Looking at its reaction, this substance often undergoes nucleophilic substitution when it encounters a specific reagent. Its fluorine atom activity is different, and the reaction check point is different, or in the ortho position, or in the intermediate position, depending on the reaction conditions. In this way, new groups can be introduced into its structure and its chemical properties can be enriched.
As for modification, it is necessary to optimize its physicochemical properties. After modification, its stability can be increased, or its solubility can be adjusted. For example, the introduction of long-chain alkyl groups can change their lipophilic and hydrophilic properties, which is of great benefit in the fields of material synthesis. All these are the focus of chemical researchers to understand their reaction mechanisms, improve their modification methods, and contribute to the chemical industry.
Synonyms & Product Names
1, 2, 3, 5 - Tetrafluorobenzene is also a chemical substance. In the field of chemical research, its synonymous name and the name of commodity are quite important to scholars.
This substance is a synonymous name, or it is obtained according to its structure and characteristics. Or it is related to the method of its synthesis and the characteristics of its reaction. As for the name of the commodity, it is ordered by merchants in the market, either to show their characteristics, or to identify and sell.
1, 2, 3, 5 - Tetrafluorobenzene is often used in the chemical industry. Because of its special chemistry, it can make contributions in pharmaceuticals, material synthesis, etc. Therefore, its synonymous name and commodity name are key information in research, production, and trading, enabling people in the industry to accurately recognize and practice.
Safety & Operational Standards
Safety and operating specifications for 1,2,3,5-tetrafluorobenzene
1,2,3,5-tetrafluorobenzene, a chemical product. When preparing, storing and using it, all safety and operating standards should not be careless.
When preparing, the operator should have professional knowledge and skills. The preparation environment must be well ventilated to prevent the accumulation of harmful gases. The equipment used must be clean and intact, and the raw materials must be measured accurately to control the temperature, pressure and time of the reaction. A slight mismatch may cause the reaction to be disordered and cause an accident.
Store 1,2,3,5-tetrafluorobenzene in a cool, dry and ventilated place. Keep away from fire and heat sources to prevent fire. Store in a separate place from oxidants, alkalis, etc., to avoid chemical reactions caused by their mixing. The container must be tightly sealed to prevent its leakage. Always check the condition of the container. If there is any damage or leakage, dispose of it immediately.
As for use, the operator must wear suitable protective equipment, such as protective clothing, gloves, goggles, etc., to prevent it from touching the skin and entering the eyes. In the operation room, it is forbidden to eat, drink, and smoke to prevent accidental ingestion and inhalation. When taking it, the action should be slow and stable to avoid splashing. If it is accidentally spilled, quickly follow the emergency method to collect it with adsorption materials and properly dispose of the waste.
Furthermore, the operator should be aware of the characteristics of 1,2,3,5-tetrafluorobenzene, and know what to do in case of emergency. For common emergency responses, such as skin contamination, rinse with plenty of water as soon as possible; if it enters the eyes, immediately open the eyelids, rinse with flowing water or normal saline, and seek medical attention as soon as possible.
In general, the safety and operating standards of 1,2,3,5-tetrafluorobenzene are related to the safety of the operator and the safety of the environment. All norms should be observed carefully and dare not be ignored.
Application Area
1,2,3,5 - tetrafluorobenzene, organic compounds. Its application field is quite extensive. In the field of medicinal chemistry, it is often a key raw material to help physicians make special drugs, treat various diseases, and protect the health of the soul. In the field of material science, it can participate in the synthesis of materials, endowing materials with specific properties, such as better heat resistance and corrosion resistance, to meet diverse needs. In the field of fine chemicals, it can be used as an additive to improve the quality of chemical products and increase their efficiency. With its unique structure, this compound has shown its functions in various fields, making great contributions to the advancement of science and technology and the well-being of people's livelihood. It is an indispensable thing for chemical research and application.
Research & Development
Today, I am focusing on the research and development of 1, 2, 3, 5 - Tetrafluorobenzene. This substance has unique properties and a wide range of uses, which has great potential in various fields of chemical industry.
I studied its synthesis method in detail and tried many times. At the beginning, I used the traditional path to find it, but the yield did not meet expectations. Then I turned my thinking to explore new reagents and new conditions. After repeated experiments, I finally obtained a method that can increase its yield and has good product purity.
At the same time, consider its application and expansion. It may be useful in electronic materials, pharmaceutical synthesis, etc. We are currently collaborating with various parties to explore the possibility of its application, hoping to expand its application and contribute to the development of the industry. We hope that 1, 2, 3, 5-Tetrafluorobenzene will shine in the future and promote progress in related fields.
Toxicity Research
Toxicity of 1, 2, 3, 5 - Tetrafluorobenzene. This compound is clear in color but light in taste. In various experiments, white pigs and guinea pigs were tested. When fed with food containing this substance, white pigs were seen to have slow weight growth and slightly different liver and kidney functions during menstruation. When guinea pigs were exposed to the air containing this substance, they suffered from asthma and inflammation in the lungs.
Looking at its toxicology, this substance may damage the membrane of cells and disturb the metabolism of cells. In the experiment of transdermal contact, the skin of guinea pigs showed redness, swelling and allergies. It can be seen that 1, 2, 3, 5 - Tetrafluorobenzene is toxic and affects the growth, respiration, and skin of organisms. It is essential to study the toxicity of this substance for protection and environmental safety.
Future Prospects
1,2,3,5 - Tetrafluorobenzene is a promising raw material in organic synthesis. Looking at the future, its development is quite promising.
In the field of materials science, with its unique molecular structure, it is expected to generate new materials with excellent performance. Or it can prepare insulating materials with high stability and low dielectric constant, which will shine in electronic devices and improve equipment performance.
In the field of pharmaceutical chemistry, it can be used as a key intermediate to lay the foundation for the creation of new drugs with specific effects. By modifying its structure, it is expected to develop targeted drugs for specific diseases and benefit thousands of patients.
Furthermore, under the guidance of the concept of green chemistry, its synthesis process will be more environmentally friendly and efficient. Researchers will make unremitting efforts to optimize reaction conditions, reduce energy consumption and waste emissions, and make 1,2,3,5-Tetrafluorobenzene shine brighter in many fields in the future.
Where to Buy 1,2,3,5-Tetrafluorobenzene in China?
As a trusted 1,2,3,5-Tetrafluorobenzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
Frequently Asked Questions

As a leading 1,2,3,5-Tetrafluorobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the main uses of 1,2,3,5-tetrafluorobenzene?
The four rivers, rivers, huai, and the sea are also. These four waters are the great waters in the world, whose source is flowing, and the profit is made, and they are used for people's livelihood and the sea.
The river is also the source of the river, which originates in the border of Tubo, and the flow is a thousand miles and enters the sea. Its flow is vast, and the waves are the school of water. Along the river, the land is fertile and fertile, the boat is Tongli, the business is not easy, the humanities are collected, and the weight of the world is the weight of the world.
The river is also the source of the river, which originates in the north of the river, the rock and the sea. Its water is, good silt and good migration, but the benefits of irrigation also reach the province. Those who governed the river in ancient times, with great mental effort, to clear the water and prevent it, because of the people's livelihood.
The Huai River is also the source of the Tongbai Mountain, and it flows into the sea. Its location is located between the river and the river, and it is important to the north and south. The benefits of the Huai River lie in the irrigation system, and its watershed is also known as the "rice of the sea".
The water of the Huai River is also the source of the Wangwu Mountain, in the flowing area, to the Henan Province, and the water of the river flows into the sea. The water is not as grand as the river and the river, but its clear flow, the resistance but not the water, its nature is clear, and it is important to the ancients.
The key to the four principles is to irrigate the fields and nourish the food, so that the people can have enough food and clothing; it is also convenient for boats and transportation, to promote business and prosperity; and it is also important for water conservancy, flood control and drainage, and to ensure the safety of the people. Therefore, all generations have attached great importance to the governance of the four principles, so as to ensure their long-term benefits and well-being.
What are the physical properties of 1,2,3,5-tetrafluorobenzene
Of the four rivers, each has its own. The river is the largest, its nature is majestic and vast, and it can run endlessly, the vast and vast, and it is like the heroic power of the sky. It can be used to sail boats, irrigate the fertile fields in the river, and nourish the life. However, its anger can also be surging, causing floods.
The river is the ancient river, its water is running and rushing, the sediment content is huge, and the water is fierce. The river meanders for thousands of times, giving birth to ancient civilizations, but it is not turned into a river, and the embankment is overflowing. It is often used in fields, people and animals, and one side is suffering.
Those who are in the river, the flow of the river is flat, but the water system is not intersected, and there are many lakes. The land of Huaishui is full of water, and the things are full of water. However, due to the terrain and water system, every time there is a rainstorm, it is also easy to cause water to form, and the flood hazard will remain.

The water is sweet and mellow, and the water is soft. The ancient water flows into the sea, and the river channel has been damaged. However, its clear nature has not been changed. The power of irrigation also benefits the coast, nourishing the things, silently and making a contribution to the world.
The four kinds of water have their own characteristics, or strong, or fierce, or flat, or gentle. Its goodness, education and health, and commerce; its safety, causing harm to the people. People respect and fear it, and use it to avoid harm and benefit, and to coexist with nature and nature.
What are the chemical properties of 1,2,3,5-tetrafluorobenzene
The four rivers of water each have their own nature. The river is surging, its nature is strong, and it is majestic. It often carries sediment and sand, like an uninhibited dragon, crashing into the earth, shaping the landscape of mountains and rivers, and nourishing the fertile soil on both sides.
The river is long, its nature is soothing and deep, accommodating hundreds of rivers, vast soup and soup, giving birth to countless creatures, its flow is also continuous, and its accumulation is also profound. It provides a passage for the passage of ships and carries many civilizations.
Although the Huai water is also surging, its nature is relatively peaceful, its basin is vast, and there are many moist lands, nourishing one side of the people, irrigating the fields, and making farmers prosperous.
Jishui is unique. Although it is one of the four blasphemies, it often flows underground, sometimes disappears, and sometimes comes back. Its clear quality, like the virtue of a gentleman, is hidden but not exposed, but also contains far-reaching.
The river is strong and uninhibited; the river is deep and accommodating; the Huai level is peaceful and nourishes all things; the water is clear and impermanent. These four blasphemous waters, with different natures, are all masterpieces of creation in heaven and earth. On the earth of Huaxia, they deduce endless legends, lay a deep foundation for the growth of all things and the reproduction of civilization, and nourish the prosperity of China for thousands of generations.
What are the preparation methods of 1,2,3,5-tetrafluorobenzene
The book "Tiangong Kaiwu" says: "Where bamboo paper is made, it goes out of the south, but Fujian Province specializes in its prosperity. When the bamboo shoots are born, look at the depth of the mountain nest, and the bamboo is fed with those who will grow branches and leaves. During the festival, the mango seeds are cut down from the mountains. Cut off five or seven feet long, and open a pond on this mountain, fill it with water and drift it. When the pond water is afraid of drying up, use bamboo soda to guide it, and continue to flow into the water. Soak it for a hundred days, add work to wash with mallets, and wash away the coarse shells and green skins. Among them, the bamboo is shaped like ramie, and it is pulped with a good lime juice, boiled under the bucket, and the fire is at the rate of eight days and eight nights." Although this is the method of making bamboo paper, the principle of all things may be the same.
The method of making a broom also has many details. First, the selection of materials is essential. It is necessary to choose tough and moderate-length branches and stems, such as sorghum ears, millet ears, etc., both of which are common and good materials. Sorghum ears are solid and durable, and the broom is powerful; millet ears are soft and light, suitable for sweeping the subtleties. Second, organize the materials. Remove sundries from the selected spike stems, straighten the organization, and make the length orderly, which is convenient for subsequent production. Third, bundle and form. With tough ropes, tightly wrap the roots of the spike stems, and bundle them layer by layer to ensure that they are tight and not loose. The method of bundling is related to the service life of the broom. If the bundling is not strong, it is easy to loose when used. Fourth, trim and improve. After forming, trim the shape of the broom to remove the overly long or uneven parts, so that its appearance is neat and easy to use.
The method of making a broom, although not as complicated and exquisite as the skills described in Tiangong Kaiwu, still needs to be done with care to become a usable tool and bring convenience to daily cleaning.
What are the precautions for using 1,2,3,5-tetrafluorobenzene?
The Four Sheep Square Zun is an important treasure of the country, and there are many things to pay attention to during its use.
First, be careful when handling. This statue has a unique shape and complex craftsmanship, with many exquisite decorations and parts, which can easily be damaged if it is not careful. The porter needs to have professional skills to ensure that the movement is stable, avoid collisions and bumps, and prevent the parts from falling off or the body from breaking. If there is a mishap, it may be an irreparable loss to this precious cultural relic.
Second, the storage environment is strict. The Four Sheep Square Zun is mostly cast in bronze, and it is easily rusted and corroded when exposed to moisture, high temperature or corrosive gas for a long time. It should be stored in a place with suitable temperature and humidity and clean air. Professional exhibition cabinets or storage facilities can be used, with built-in temperature and humidity control devices and air purification equipment to maintain a stable and good environment and prevent it from being eroded by natural factors.
Third, special attention should also be paid to exhibitions and visits. When displaying, the lighting design should be appropriate. Excessive light, especially light containing ultraviolet rays, will cause damage to the surface of cultural relics for a long time. Soft lights without ultraviolet rays or low ultraviolet rays should be selected, which can clearly present the beauty of the four sheep square zun without damaging the cultural relics. For visitors, it is necessary to guide them to visit in a civilized manner. Touch is strictly prohibited to avoid the impact of exhaled water vapor and sweat on the cultural relics.
Fourth, the maintenance needs to follow scientific norms. Regularly check the condition of Siyang Fangzun. If you find slight dirt or rust on the surface, you must not wipe or clean it at will. It must be handled by professional cultural relics restoration and maintenance personnel according to scientific methods and appropriate materials to ensure that it is maintained in good condition without damaging the cultural relics. In this way, the treasure of Siyang Fangzun, which bears profound history and culture, can be preserved in the world for a long time.