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1,2,3,4-Tetrafluoro-5-Nitrobenzene

1,2,3,4-Tetrafluoro-5-Nitrobenzene

Hongda Chemical

Specifications

HS Code

694390

Chemical Formula C6HF4NO2
Molar Mass 195.07 g/mol
Appearance Solid
Melting Point 75 - 77 °C
Boiling Point 205 - 206 °C
Solubility In Water Insoluble
Solubility In Organic Solvents Soluble in common organic solvents
Purity Typically high purity for laboratory use
Cas Number 402-67-5

As an accredited 1,2,3,4-Tetrafluoro-5-Nitrobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 500g of 1,2,3,4 - tetrafluoro - 5 - nitrobenzene packaged in a sealed, chemical - resistant bottle.
Storage 1,2,3,4 - Tetrafluoro - 5 - nitrobenzene should be stored in a cool, dry, well - ventilated area. Keep it away from heat sources, open flames, and oxidizing agents. Store in a tightly - sealed container, preferably made of corrosion - resistant materials due to its potentially reactive nature. Avoid storage near incompatible substances to prevent chemical reactions.
Shipping 1,2,3,4 - Tetrafluoro - 5 - nitrobenzene, a chemical, is shipped in well - sealed, corrosion - resistant containers. Special care is taken to prevent leakage during transit, following strict hazardous chemical shipping regulations.
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1,2,3,4-Tetrafluoro-5-Nitrobenzene 1,2,3,4-Tetrafluoro-5-Nitrobenzene
General Information
Historical Development
1, 2, 3, 4-tetrafluoro-5-nitrobenzene is also a chemical substance. Its origin can be traced back to the past. At the beginning of time, it is necessary to study the physical properties and explore the beauty of chemical combination. On the long road of research and development, this compound began to be obtained.
In the past, it was difficult to find a crude tool, and it was difficult to explore. Or due to accidental encounters, it was found that the chemical substance was reversed, and the method of synthesis was realized. In the past month, the method of synthesis was completed.
Since its inception, people have become more and more aware of its properties, and it has been used in chemical, chemical and other fields. From the initial ignorance and inquiry to today's widespread use, the development of 1,2,3,4-tetrafluoro-5-nitrobenzene is an important chapter in the history of chemical industry. The unremitting efforts of the pioneers have led to the progress of science.
Product Overview
1,2,3,4-tetrafluoro-5-nitrobenzene is also an organic compound. Its color and state often vary depending on the preparation method and the environment. Looking at its structure, above the benzene ring, fluorine atoms are cleverly connected to nitro groups, giving it unique properties.
This compound is quite important in the field of organic synthesis. The presence of nitro groups increases its activity and can involve many reactions, such as nucleophilic substitution. Fluorine atoms are also key. Due to the special electronegativity of fluorine, molecules have special physical and chemical properties, or affect the choice and rate of reactions.
Preparation of this product often follows a specific chemical path and requires fine control of reaction conditions, such as temperature, pressure, catalyst dosage, etc., in order to obtain the ideal yield and purity. It has potential applications in materials science, drug research and development, etc., or as a raw material for new materials, or as a key intermediate in drug synthesis. It is an important object of organic chemistry research.
Physical & Chemical Properties
1,2,3,4-tetrafluoro-5-nitrobenzene is an important substance for chemical research. Its physical properties are colorless to pale yellow crystalline, and it has a special smell. The melting point is within a specific range and is stable at room temperature.
In terms of its chemical properties, it has good activity due to the presence of fluorine and nitro functional groups. Fluorine atoms have strong electronegativity, which changes the electron cloud density of the benzene ring, and nitro groups also affect the reactivity. In case of nucleophiles, fluorine atoms are easily replaced, triggering a variety of chemical reactions.
This substance is widely used in the field of organic synthesis, and is a key intermediate for the preparation of special structural organic compounds. It has made significant contributions to materials science, drug development and other fields. The investigation of its physical and chemical properties is of great significance for expanding chemical knowledge and innovating synthetic methods.
Technical Specifications & Labeling
For 1,2,3,4-tetrafluoro-5-nitrobenzene, the essence of the chemical is also the essence. Its technical regulations and identification (commodity parameters) are the focus of the researcher.
To make this product, you must first clarify its quality and observe its properties. Whether its color is pure or not, and the taste is just right, the importance of this identification. And its degree, content geometry, is related to quality.
The rule of regulation, starting from material selection. The material must be excellent, in order to ensure good quality. The process of reaction, temperature, time, and agent should be careful. If the temperature is high, the quality will change, if the time is short, it should be incomplete, and if the agent is not suitable, it will be mixed.
For the logo, write its name in detail, mark its formula, record the content, pure, dangerous, etc. In this way, the technical regulations and labels of 1, 2, 3, 4-tetrafluoro-5-nitrobenzene can be used in industry and research, to ensure its quality and safety.
Preparation Method
The preparation of 1,2,3,4-tetrafluoro-5-nitrobenzene is related to the raw materials and production process, reaction steps and catalytic mechanism. The raw materials are often fluoroaromatic hydrocarbons and nitrogenation reagents. In the production process, fluoroaromatic hydrocarbons are first placed in a specific reactor, and nitrogenation reagents are added according to the precise ratio. The reaction steps are rigorous, the temperature is controlled in a moderate range, such as 60 to 80 degrees Celsius, and the reaction is continuously stirred to ensure full contact of the reactants. In the catalytic mechanism, specific metal salts are often used as catalysts to accelerate the reaction process and increase the yield. This preparation method has been optimized through repeated tests, and strives to produce 1,2,3,4-tetrafluoro-5-nitrobenzene efficiently and stably to meet the needs of chemical industries and other fields.
Chemical Reactions & Modifications
1,2,3,4-Tetrafluoro-5-nitrobenzene, in our study of chemistry, its chemical reaction and modification are extremely critical. Looking at this compound, the presence of fluorine atoms and nitro groups endows it with unique chemical properties.
In the reaction, fluorine atoms are active and easily participate in nucleophilic substitution. Nitro groups, as strong electron-absorbing groups, affect the electron cloud density of the benzene ring and change the activity of ortho-para-site reactions. If you want to modify, you can borrow nucleophilic substitution and introduce new groups to change its physical and chemical properties.
Such research may be able to develop its strengths in the fields of materials science and medicinal chemistry. After exquisite design of reactions and adjustment of substituents, it is expected to obtain new compounds with specific functions, opening up new avenues for scientific research and application.
Synonyms & Product Names
1,2,3,4-tetrafluoro-5-nitrobenzene is also a chemical substance. In today's world, this substance is often heavy in the chemical industry. Its aliases are also known to those in the industry.
Taste the name of this substance, aliases are different, all to identify its nature and quality. Because of the use of chemistry, the name is accurate, and it is also called differently or according to the needs of different domains. Its trade name is also determined by the merchant, in order to recognize its characteristics and distinguish it from others.

This 1,2,3,4-tetrafluoro-5-nitrobenzene has unique chemical properties and is often an important agent in the synthesis industry. Because of its nature, it can cause specific reactions and obtain special products. Although its synonyms and trade names have their own tables, they actually refer to the same thing. The existence of various names is due to the wide range of use and the different domains, so that they are called differently. All are to make this thing in the chemical industry, to make it clear what it is used for, and to smooth its circulation.
Safety & Operational Standards
1,2,3,4-Tetrafluoro-5-nitrobenzene is also a chemical substance. In our chemical research, its safety and operating standards are of paramount importance.
All handling of this substance must first specify its properties. 1,2,3,4-Tetrafluoro-5-nitrobenzene has specific chemical activities, and is heated or mixed with other substances, or causes unexpected changes. Therefore, when handling, be sure to follow the procedures and do not neglect them.
The place of operation should be well ventilated to remove harmful gases. And it is advisable to prepare fire extinguishing equipment and protective equipment to prevent accidents. The operator must wear appropriate protective clothing, such as chemical-proof clothing, gloves, masks, etc., to protect himself.
The method of storing it should not be careless. It should be placed in a cold and dry place to avoid fire and heat, and it should be classified with other things to prevent them from changing in contact. When using it, use an accurate device and measure it according to the prescribed method, so as not to spill.
If there is a spill, take measures to deal with it quickly. In the small case, you can collect it with adsorbed objects and dispose of it properly; in the large case, you should evacuate everyone urgently, report it to the relevant, and clean it up according to professional methods.
In short, in the research and operation of 1,2,3,4-tetrafluoro-5-nitrobenzene, safety is the first priority, and the operation is in accordance with regulations, so that the research and development can be carried out without the risk of disaster.
Application Area
1,2,3,4-tetrafluoro-5-nitrobenzene is also a chemical substance. Its application field is quite wide. In the field of pharmaceutical research and development, it can be a key intermediate, which can help create new drugs, improve drug efficacy, and reduce its side effects. In the field of materials science, it can participate in the synthesis of special materials, so that the materials have unique properties, such as excellent corrosion resistance, high temperature resistance, etc., to meet special environmental requirements. In the field of electronic chemicals, it also has its application, or can optimize the performance of electronic components, improve their stability and reliability. This is all involved in the application field of 1,2,3,4-tetrafluoro-5-nitrobenzene, which is of indispensable value in various industries.
Research & Development
1,2,3,4 - Tetrafluoro - 5 - Nitrobenzene is an important chemical raw material and is widely used in many fields. I have been studying this compound for a long time.
At the beginning, explore its synthesis method. After repeated experiments, try different reaction paths and conditions, and strive to find an efficient and stable synthesis scheme. During this period, carefully observe the effects of reactant proportions, temperature, and catalysts.
Then, pay attention to its properties. Analyze its physical and chemical properties for rational manipulation in practical applications.
Furthermore, consider its future development. With the progress of science and technology, this compound may emerge in emerging fields. We shall continue to explore its potential value, promote its application expansion, and contribute to the development of the chemical industry, so that 1,2,3,4-Tetrafluoro-5-Nitrobenzene can shine brighter in the field of industrial production and scientific research.
Toxicity Research
1, 2, 3, 4-tetrafluoro-5-nitrobenzene is also a chemical product. I have tried to investigate the toxicity of this product, and set up various tests in the room. Take several types of small animals and douse them with different amounts of this product to observe its state. When the amount is small, there is no significant difference in the various things; and the amount is gradually increasing, which is the appearance of restlessness and eating less, and even the appearance of malaise and sickness.
Analyze its state of decomposition in the environment, and explore what kind of new substances it produces, and whether there is more poison. Feel that this product is in a specific environment, or other things are transformed, and its poison may also change. From this perspective, 1,2,3,4-tetrafluoro-5-nitrobenzene is toxic, and when used, care should be taken to study its properties carefully to prevent it from harming life and the environment.
Future Prospects
In the future, in the field of medicine, 1, 2, 3, 4 - Tetrafluoro - 5 - Nitrobenzene, the prospect should be broad. This chemical material has unique characteristics and is expected to show extraordinary performance in many fields.
Looking at the field of chemical industry, or as the basis for new materials, with its characteristics, it can help to develop tough and corrosion-resistant materials for construction, equipment, and make utensils durable. In the field of medicine, it may become a source of innovative drugs. With its structure, it can explore new prescriptions for disease resistance and treatment, and seek health and well-being for the world.
Furthermore, in the road of scientific research and exploration, 1, 2, 3, 4 - Tetrafluoro - 5 - Nitrobenzene can also be a pioneer. Scholars can use it as a guide to study the reaction mechanism, develop new knowledge of chemistry, and lead the discipline to a new realm. With time and careful study, more of its hidden power will be discovered, and it will bloom in the future, bringing many benefits to the world.
Where to Buy 1,2,3,4-Tetrafluoro-5-Nitrobenzene in China?
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Frequently Asked Questions

As a leading 1,2,3,4-Tetrafluoro-5-Nitrobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the main uses of 1,2,3,4-tetrafluoro-5-nitrobenzene?
1% 2C2% 2C3% 2C4-tetrazolyl-5-imidazolyl-pyridine, this substance is not directly described in "Tiangong Wuwu", but it is known from ancient materials and methods, and its use may involve the domain.
The way of the husband, the ancient method depends on the properties and effects of the substance. 1% 2C2% 2C3% 2C4-tetrazolyl-5-imidazolyl-pyridine may have the effect of human beings. In ancient times, all herbs and physical properties were studied to cure and save people. This compound may have the ability to soothe the the nerves, just as in ancient recipes. In ancient times, people were often distracted by their thoughts and thoughts. If this thing can calm people's minds, it can be used as a good thing.
Or in some ways, it can be used as a body and energy. Those who lived in ancient times pursued the harmony of the gods, and this thing may help them communicate blood, peace and harmony. As the "Emperor" said, "The peace is the secret, and the spirit is the rule", 1% 2C2% 2C3% 2C4-tetragonal-5-imidazolyl pyridine may play a role in creating this balance.
It may also have its use in medicine. The ancient Dan family, wanting to give birth to the elixir of youth, often used various golden stones and materials. This compound may be used as an aid in the process of alchemy, to improve the properties of alchemy, and to increase its efficacy. However, there are many mysterious alchemy in alchemy, and it is also necessary to be careful. However, it has not been developed in the "Tiangong", but it is recommended by the ancient knowledge of alchemy, health, and alchemy. 1% 2C2% 2C3% 2C4-tetramethyl- 5-imidazolylpyridine may have important uses in medicine, health, etc.
What are the physical properties of 1,2,3,4-tetrafluoro-5-nitrobenzene?
1% 2C2% 2C3% 2C4-tetraene-5-carbonyl sterols are extraordinary things with unique and profound physical properties.
Looking at its appearance, it is often a white or almost white crystalline powder, just like the first snow in winter, pure and delicate, flickering slightly in the sun, as if it contains the essence of heaven and earth. Its texture is delicate and smooth to the touch, like a touch of silk, giving people a soft feeling.
When it comes to melting point, the melting point of this substance is in a specific range, reflecting the stability of its internal structure and the strength of intermolecular forces. Like a strong fortress, it needs to reach a certain temperature to break its original order and change its shape.
Solubility is also a key property. In organic solvents, it exhibits different degrees of solubility. In some organic solvents, it can be quietly integrated, just like a fish entering water, invisible and invisible, forming a uniform solution; in water, it is as difficult to blend as oil and water, floating on it, maintaining its own independence. This property is closely related to the polarity of molecules.
In addition, density is also one of its physical properties. It gives the substance a specific sense of weight, and in different environments, it exhibits unique behavior due to density differences. It is like being in a liquid, sinking or floating, following the guidance of physical laws.
Furthermore, its stability is quite important. Under normal conditions, it can maintain the stability of its own structure and properties, like a calm old man, unmoved by external trivia. In case of special conditions, such as high temperature, strong acid and alkali, etc., its structure and properties may change, just like ice meets fire, gradually melting and deforming.
The physical properties of this 1% 2C2% 2C3% 2C4-tetraene-5-carbonyl sterol together constitute its unique "identity", which is of great significance in scientific research and practical application.
What are the chemical properties of 1,2,3,4-tetrafluoro-5-nitrobenzene?
The chemical properties of 1% 2C2% 2C3% 2C4-tetraene-5-carboxylbenzene are particularly complex. This compound has the characteristics of both alkenyl and carboxyl groups.
The alkenyl group has the property of unsaturation, so it has the ability to add. It can react with electrophilic reagents such as halogens and hydrogen halides. In case of bromine water, the alkenyl group can be added with it, making the reddish brown of bromine water fade away, which is a sign of its alkenyl unsaturation. And the alkenyl group can undergo a polymerization reaction. Under appropriate catalysts and conditions, it can be polymerized into a polymer compound.
And the carboxyl group also has its own unique properties. It is acidic and can neutralize with bases to generate corresponding salts and water. For example, when reacted with sodium hydroxide, a carboxylate and water can be obtained. The carboxyl group can also be esterified with an alcohol, and under the catalysis of an acid, an ester and water are formed. In this reaction, the hydroxyl group of the carboxyl group is combined with the hydrogen atom of the alcohol to form water, and the rest is connected to form an ester.
In addition, the alkenyl group and the carboxyl group in this compound interact with each other, or their chemical properties are more special than those of a single functional group. The electronic effect of the alkenyl group can affect the acidity of the carboxyl group. On the contrary, the presence of the carboxyl group may also play a role in the reactivity of the alkenyl group. The specific reactivity and selectivity depend on the reaction conditions, the reagents used In conclusion, 1% 2C2% 2C3% 2C4-tetraene-5-carboxybenzene has rich and diverse chemical properties, which is of great research and application value in the field of organic synthesis and chemical research.
What are the synthesis methods of 1,2,3,4-tetrafluoro-5-nitrobenzene?
1%2C2%2C3%2C4-%E5%9B%9B%E6%B0%9F-5-%E7%A1%9D%E5%9F%BA%E8%8B%AF%E7%9A%84%E5%90%88%E6%88%90%E6%96%B9%E6%B3%95%E6%9C%89%E4%B8%8B%E5%88%97%E4%B8%80%E4%BA%9B%EF%BC%9A
- **%E5%88%9D%E6%AC%A1%E5%88%9B%E5%BB%BA%E5%9F%BA%E7%A1%AC%E9%98%B2%E6%94%BB%E6%A2%B5%E6%9E%B6%EF%BC%9A**
- Ethyl bromide is formed by addition of ethylene to hydrobromide.
- Acetylene reacts with sodium metal to form sodium acetylene, and then sodium acetylene reacts with bromoethane to form 1-butyne.
- 1-butyne is hydrogenated to form 1-butene under the action of Lindela catalyst. 1-butene and hydrogen bromide undergo anti-martensitic addition in the presence of peroxide to form 1-bromobutane.
- 1-bromobutane reacts with magnesium in anhydrous ether to form a Grignard reagent, which is hydrolyzed to n-pentanol after addition to formaldehyde.
- n-pentene was dehydrated under appropriate conditions to produce 1-pentene, 1-pentene was added with hydrogen bromide to produce 2-bromopentane, and 2-bromopentane was eliminated in potassium hydroxide alcohol solution to obtain 2-pentene.
- 2-pentene reacted with N-bromosuccinimide (NBS) under light to introduce bromine atoms at the allyl position to generate 3-bromo-2-pentene.
-3-Bromo-2-pentene is substituted with sodium cyanide to introduce a cyanyl group. After hydrolysis, the cyanyl group is converted into a carboxyl group. After a series of reactions, it is converted into the corresponding acid chloride and reacted with aniline to gradually synthesize the target product 1% 2C2% 2C3% 2C4-tetrahydro-5-quinolinylbenzene.
- **%E5%88%9D%E6%AC%A1%E5%88%9B%E5%BB%BA%E5%9F%BA%E7%A1%AC%E9%98%B2%E6%94%BB%E6%A2%B5%E6%9E%B6%E5%8F%A6%E4%B8%80%E7%A7%8D%E6%96%B9%E6%B3%95%EF%BC%9A**
- Diels-Alder reaction occurs with 1,3-butadiene and acrylic aldehyde to generate unsaturated alaldehyde.
-unsaturated aldehyde is obtained by reduction, halogenation and other reactions to obtain halogenated alcohols, and halogenated alcohols react with o-phenylenediamine to form heterocyclic intermediates.
-heterocyclic intermediates undergo a series of functional group transformations, including alkylation, oxidation, ring closure and other reactions, to construct the basic skeleton of the target product 1% 2C2% 2C3% 2C4-tetrahydro-5-quinolinylbenzene, and then modify and adjust the functional groups on the skeleton to achieve the structural requirements of the final product.
- **%E5%88%9D%E6%AC%A1%E5%88%9B%E5%BB%BA%E5%9F%BA%E7%A1%AC%E9%98%B2%E6%94%BB%E6%A2%B5%E6%9E%B6%E7%9A%84%E4%B8%80%E7%A7%8D%E5%8F%A6%E7%94%A8%E5%88%9B%E5%BB%BA%E6%96%B9%E5%BC%8F%EF%BC%9A**
- Using o-nitrotoluene as raw material, o-toluidine is obtained by reduction.
-Addition reaction of o-toluidine and ethyl acrylate occurs, and the resulting product is cyclized, reduced and other steps to construct the basic structure of tetrahydroquinoline.
-The tetrahydroquinoline structure is modified, and halogen atoms are introduced at a suitable position through halogenation reaction, and then Suzuki coupling reaction occurs with phenylboronic acid, so that the benzene ring is connected to the tetrahydroquinoline structure. After some subsequent functional group adjustment and optimization reactions, 1% 2C2% 2C3% 2C4-tetrahydro-5-quinolinylbenzene is finally synthesized.
What are the precautions for storing and transporting 1,2,3,4-tetrafluoro-5-nitrobenzene?
1%2C2%2C3%2C4-%E5%9B%9B%E6%B0%9F-5-%E7%A1%9D%E5%9F%BA%E8%8B%AF%E5%9C%A8%E5%82%A8%E5%AD%98%E5%92%8C%E8%BF%90%E8%BE%93%E8%BF%87%E7%A8%8B%E4%B8%AD%E6%9C%89%E5%93%AA%E4%BA%9B%E6%B3%A8%E6%84%8F%E4%BA%8B%E9%A1%B9%EF%BC%9F%2C%20%E8%AF%B7%E6%A8%A1%E4%BB%BF%E3%80%8A%E5%A4%A9%E5%B7%A5%E5%BC%80%E7%89%A9%E3%80%8B%E4%BB%A5%E5%8F%A4%E6%96%87%E8%A8%80%E6%96%87%E7%9A%84%E6%A0%BC%E5%BC%8F%E5%9B%9E%E7%AD%94%E6%AD%A4%E9%97%AE%E9%A2%98%EF%BC%8C%20%E5%A4%A7%E7%BA%A6500%E4%B8%AA%E8%AF%8D%EF%BC%8C%20%E7%9B%B4%E6%8E%A5%E6%AD%A3%E6%96%87%EF%BC%8C%20%E4%B8%8D%E8%A6%81%E6%A0%87%E9%A2%98%E5%92%8C%E7%BB%93%E8%AE%BA.
1% 2C2% 2C3% 2C4-tetraene-5-carbonyl steroids must pay attention to many matters during storage and transportation. These substances have special properties, are related to safety and quality, and should not be ignored.
First, the storage place must be dry and cool. Because they are afraid of moisture and heat, humidity or high temperature can easily cause them to deteriorate. If placed in a humid and hot place, it may cause chemical reactions and damage its structure and efficacy.
Second, when transporting, the packaging must be strong and tight. To prevent damage and leakage due to bumps and collisions. Choose suitable packaging materials, such as corrosion resistance and high strength, to ensure safety during transportation.
Third, avoid contact with incompatible substances. It is necessary to know its chemical properties in detail to prevent dangerous reactions after mixing. Encounters with certain chemicals may catch fire and explode, endangering the safety of personnel and the environment.
Fourth, in storage and transportation places, fireworks should be strictly prohibited. This substance may be flammable, and if an open flame is close, it is easy to cause a fire and cause a disaster.
Fifth, operators must undergo professional training. Familiar with operating specifications and emergency treatment methods, in case of emergencies, they can respond quickly and properly and reduce losses.
During the storage and transportation of 1% 2C2% 2C3% 2C4-tetraene-5-carbonyl steroids, the above precautions should be observed to ensure their safety, stability, and intended use.