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1-(1-Bromoethyl)-3-(Trifluoromethyl)Benzene

1-(1-Bromoethyl)-3-(Trifluoromethyl)Benzene

Hongda Chemical

Specifications

HS Code

748230

Chemical Formula C9H8BrF3
Molar Mass 253.06 g/mol
Appearance Liquid (usually)
Boiling Point Data may vary, around certain temperature related to its structure
Melting Point Data may vary depending on purity etc.
Density Data may vary based on conditions
Solubility Solubility characteristics in common solvents like organic solvents
Vapor Pressure Value depends on temperature
Flash Point Depends on conditions
Stability Stability under normal conditions and potential reactivity with certain substances
Packing & Storage
Packing 100g of 1-(1 - bromoethyl)-3-(trifluoromethyl)benzene in a sealed, chemical - resistant bottle.
Storage 1-(1 - bromoethyl)-3-(trifluoromethyl)benzene should be stored in a cool, well - ventilated area, away from heat sources and open flames. Keep it in a tightly closed container, preferably made of corrosion - resistant materials. Store it separately from oxidizing agents and incompatible substances to prevent potential reactions. Avoid exposure to moisture and direct sunlight.
Shipping 1-(1 - bromoethyl)-3-(trifluoromethyl)benzene is shipped in specialized, leak - proof containers. It adheres to strict chemical shipping regulations, ensuring safe transport to prevent any risks associated with its potentially hazardous nature.
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1-(1-Bromoethyl)-3-(Trifluoromethyl)Benzene 1-(1-Bromoethyl)-3-(Trifluoromethyl)Benzene
General Information
Historical Development
1- (1 -bromoethyl) -3- (trifluoromethyl) benzene is also an organic compound. Its initial research began with Zhu Xian's deepening of halogenated aromatics. At that time, scholars were committed to expanding the scope and properties of aromatic hydrocarbon derivatives.
At the beginning, the synthesis method was quite difficult and the yield was not good. However, the public worked tirelessly, and after years of hard work, they improved their skills. Or optimize the reaction conditions, adjust the temperature, pressure and catalyst; or find a new reaction path to simplify the process.
Years passed, and the synthesis method became more and more mature, the yield gradually increased, and the purity was also excellent. Then it emerged in the fields of organic synthesis, medical chemistry, etc., and became an indispensable raw material and intermediate. Its development process is a testament to the diligent research and innovation of scholars, paving the way for the subsequent exploration of organic compounds.
Product Overview
1- (1 -bromoethyl) -3- (trifluoromethyl) benzene is an organic compound. Its color is clear, like a liquid flow, with a special smell.
In this compound, the structure of the benzene ring is stable, with 1-bromoethyl at the 1st position and trifluoromethyl at the 3rd position. Its physical properties, melting point depends on the intermolecular force, and its solubility is quite good in organic solvents. It is insoluble in water, and it is a non-polar molecule.
Chemical properties are active, bromine atoms on bromoethyl groups are highly active, and nucleophilic substitution reactions are prone to occur. In case of nucleophilic reagents, bromine atoms can be replaced to form new compounds. Trifluoromethyl has strong electron absorbency, which affects the electron cloud density of the benzene ring, decreases the electron cloud density of the ortho-para-site of the benzene ring, and increases the relative increase of the meta-site, which in turn affects the activity and positional selectivity of its electrophilic substitution reaction.
It has a wide range of uses in the field of organic synthesis and can be used as an intermediate. It can construct complex organic molecules through various reactions, and has potential application value in many fields such as medicine and pesticides.
Physical & Chemical Properties
1 - (1 -bromoethyl) -3 - (trifluoromethyl) benzene, its physical and chemical properties are very critical. This compound has a specific color state, and it is colorless to pale yellow liquid at room temperature, and it is clear and transparent. Its boiling point and melting point are also characterized. The boiling point is about a certain temperature range, and the melting point is at the corresponding value, which is related to the transformation of its phase state.
In terms of solubility, it may have some solubility in organic solvents, but it is not well soluble in water. As for chemical properties, the presence of bromine atoms and trifluoromethyl in its molecular structure gives it unique reactivity. Bromine atoms can participate in nucleophilic substitution reactions, while trifluoromethyl affects the electron cloud distribution of molecules, which makes the compound show different uses in the field of organic synthesis and provides an important basic property basis for chemical research and production.
Technical Specifications & Labeling
1 - (1 -bromoethyl) -3 - (trifluoromethyl) benzene is an important material involved in the development of chemical industry. Its process specifications and identification (commodity parameters) are related to the quality and use of this product, which cannot be ignored.
To make this product, a specific method needs to be followed. The choice of raw materials must be pure, and the reaction temperature, time, and proportion of agent are all key. Its process specifications specify the degree of operation of each step, such as the temperature of the reactor. When controlled in a certain range, if it is too high, the product will be volatile, and if it is too low, the reaction will be slow. The
logo (commodity parameters) cannot be ignored either. From the color state of the appearance to the standard value of purity, it is a proof of quality. If the color does not match, or contains impurities; if the purity is not reached, the efficiency will be reduced. The two, process specifications and labels (commodity parameters), complement each other, and are the best products of 1 - (1 - bromoethyl) -3 - (trifluoromethyl) benzene, building the foundation.
Preparation Method
The preparation method of 1- (1-bromoethyl) -3- (trifluoromethyl) benzene is related to the raw material and production process, reaction steps and catalytic mechanism. Its preparation is sequentially reacted with specific raw materials. First take the raw material containing the benzene ring and react with the brominating reagent under suitable conditions. This step requires temperature control and reaction time to make the bromine atom precisely replace the hydrogen atom at a specific position in the benzene ring. The brominating reagent used is selected according to the reaction characteristics to ensure the efficient and high selectivity of the reaction.
Then, a reagent containing trifluoromethyl is introduced, and the trifluoromethyl is successfully connected to another position in the benzene ring by means of a specific catalytic mechanism. The catalytic mechanism of this process is crucial, and it may involve metal catalysis or acid-base catalysis to reduce the activation energy of the reaction and accelerate the reaction process.
Between each reaction step, it is necessary to properly handle the intermediate to ensure its purity and stability, and lay the foundation for the subsequent reaction. After multiple steps of precise operation, 1- (1-bromoethyl) -3- (trifluoromethyl) benzene is finally obtained. This preparation method can effectively obtain this product, which is of great value in the field of organic synthesis.
Chemical Reactions & Modifications
I have tried to study the reaction properties of 1- (1 - Bromoethyl) -3- (Trifluoromethyl) Benzene. The common reaction of this compound is the substitution of its bromine atom with other substances. In the past, the reaction results were harsh, and the reaction rate was not ideal.

Those who are husband, I am looking for it. If you want to improve it now, you can improve the reaction properties and catalytic effects, and improve the reaction properties. In this way, it may be able to promote its reaction properties, increase the reaction rate, and control its reaction properties.
And its chemical properties, because it contains trifluoromethyl, have special properties. Its reaction effect, affecting the activity of molecules. Research makes it clear, or it can be used in the field of new research and material synthesis, so it is useful. Therefore, the study of the anti-chemical properties of this compound is of deep significance in the process of transformation.
Synonyms & Product Names
1 - (1 - bromoethyl) -3 - (trifluoromethyl) benzene, the synonym and trade name of this substance, is quite worth exploring. In the process of my chemical research, the different names of each substance are like hidden clues, guiding in-depth exploration.
Guanfu 1 - (1 - bromoethyl) -3 - (trifluoromethyl) benzene, its synonyms may come from different perspectives in the research process. Or because of the structure analysis, according to its atomic arrangement characteristics, it gets a different name. And the trade name is often related to marketing activities and application scenarios. In order to make their products stand out, merchants give unique names and hope to recognize their characteristics in the industry.
In other words, exploring its synonyms and trade names can give insight into the development of the chemical field. The naming habits of different research teams in different periods reflect the cognitive level and research focus at that time. For example, ancient books contain objects, names change with the world, and so do the names of chemical substances, which connect the chain of knowledge inheritance and innovation. In the scientific research journey, it illuminates the way forward for our generation, and helps to fully understand and apply 1- (1-bromoethyl) -3 - (trifluoromethyl) benzene.
Safety & Operational Standards
Safety and Handling Specifications for 1- (1-bromoethyl) -3- (trifluoromethyl) benzene
V 1- (1-bromoethyl) -3- (trifluoromethyl) benzene is an important substance in chemical research. During its experimental operation and research process, safety and operating standards are of paramount importance.
In terms of safety, this substance is dangerous. The presence of its bromine atom and trifluoromethyl can cause harm when exposed to human body. Therefore, researchers need to wear appropriate protective equipment, such as laboratory clothes, gloves and protective goggles, to prevent skin contact and splashing into the eyes. And because of its possible volatilization, the experiment should be carried out in a well-ventilated environment. A fume hood should be set up to remove the volatile gas in time to prevent it from accumulating in the air and endangering the health of the researcher.
In terms of operating specifications, use this substance with caution. Take the required amount accurately, do not waste it, and prevent excessive experimental deviation. During the transfer process, use suitable equipment to avoid spills. If there is a spill, clean it up immediately according to specific procedures, and do not slack.
When storing, it should be placed in a cool, dry and ventilated place, away from fire sources and oxidants. Due to its active chemical nature, improper storage or reaction can cause safety accidents.
Furthermore, before and after the experiment, the equipment used should be properly cleaned and disposed of to prevent residual substances from affecting the follow-up experiment or causing pollution to the environment.
In short, in the research operation of 1- (1-bromoethyl) -3- (trifluoromethyl) benzene, strict adherence to safety and operating standards is a necessary measure to ensure the smooth research, ensure the safety of researchers and protect the environment, and must not be taken lightly.
Application Area
1- (1 -bromoethyl) -3- (trifluoromethyl) benzene, the application field of this substance is very critical. In the field of organic synthesis, it is often used as a key intermediate. It can be converted into a variety of organic compounds with unique properties through ingenious chemical reactions.
According to Guan Fu's past family, such compounds are often at the heart of creating drug molecules with special structures. Because of its unique chemical structure, it can introduce specific functional groups to help drugs act precisely on targets.
In the field of materials science, it may be able to participate in the synthesis of novel functional materials. With its fluorine and bromine atomic properties, it may endow materials with special electrical and optical properties. For example, the synthesis of materials with special electrical conductivity or optical response can take advantage of the unique structural advantages of this compound. In fact, in many application fields, there are unlimited potential, waiting for our in-depth exploration.
Research & Development
In recent years, chemical substances have been studied, with particular attention to (1- (bromoethyl)) -3- (trifluoromethyl) benzene. At the beginning, explore the method of its synthesis, go through various attempts, through the selection of reagents and the adjustment of conditions, and gradually reach a feasible path. The synthesis process is fine and careful, and every step is about success or failure.
Then, observe its properties, observe its physical state, measure its chemical properties, and record data in detail to clarify its characteristics. Its performance in various reactions lays the foundation for subsequent applications.
At this time, I hope to use this substance as a basis to expand its application field. Or used for the creation of new drugs, or for material innovation. With unremitting research, this product has made progress in scientific research and industry, so as to become a great cause of development and add brilliance to the path of chemistry.
Toxicity Research
Since modern times, chemical refinement has led to the emergence of all kinds of new substances. Today, there is 1- (1-bromoethyl) -3- (trifluoromethyl) benzene, which is quite important for toxicity research.
We study it and observe its properties in detail. It changes under various environments, all of which are in my eyes. Observe its harmony with other things, and observe its impact on living things. Whether it touches the skin or enters the breath, there are different responses.
After many tests, we can know the approximate toxicity of it. Although it is not fully understood, it has already been revealed. It has the ability to damage the cells of living things; it also has the effect of interfering with various physiological functions.
Toxicity research is not a one-day effort. In the future, we should go deeper to clarify the details, and use this substance for the world to avoid its harm and guide its benefits. It is the responsibility of our generation of chemical researchers.
Future Prospects
I have tried to research 1- (1-bromoethyl) -3- (trifluoromethyl) benzene, which has unique properties and a wide range of uses. Looking at today's chemical industry, the demand is growing and the prospect is promising.
The future development is expected to improve the synthesis method. Or find a simpler and more efficient way to reduce its cost and increase its yield. And with the advancement of technology, the detection technology will also be more refined, and its structure and characteristics can be more accurately analyzed.
At the application end, it is expected that it will play a great role in the fields of medicine and materials. In medicine, it may be a key component of new pharmaceuticals; in materials, it may help to develop new materials with specific properties. This is my vision for the future of 1- (1-bromoethyl) -3- (trifluoromethyl) benzene, hoping that it will flourish in various industries and contribute to the world.
Frequently Asked Questions
What are the main uses of 1- (1-bromoethyl) -3- (trifluoromethyl) benzene?
1 - (1 - hydroxyethyl) - 3 - (triethylamino) benzene, its main uses are as follows:
This compound is often used as a key intermediate in the field of organic synthesis. In the field of pharmaceutical chemistry, with its unique chemical structure, it can participate in the construction of many drug molecules. For example, in the development of some drugs with specific physiological activities, it can be used as an important starting material to introduce specific functional groups through a series of chemical reactions, and then shape the drug structure that meets the needs of the target, laying the foundation for the creation of new therapeutic drugs.
In the field of materials science, it also has outstanding performance. Due to its structural properties, it can be added to specific material systems as a modifier. For example, the introduction of this substance in some polymer materials can effectively adjust the physical and chemical properties of the material, such as improving the solubility of the material, improving the stability of the material and optimizing the surface properties of the material, thereby expanding the application range and practical value of the material.
In the field of catalysis, 1- (1-hydroxyethyl) -3- (triethylamino) benzene has also emerged. It can be used as a ligand to combine with metal ions to form a metal complex catalyst with unique properties. Such catalysts exhibit high catalytic activity and good selectivity in many organic reactions, can significantly reduce the severity of reaction conditions, improve reaction efficiency and product purity, and are of great significance in chemical production and organic synthesis process optimization.
In addition, it is also one of the commonly used raw materials in the preparation of fine chemicals. Through ingenious chemical reactions, various fine chemicals with special functions can be derived, such as special surfactants, fragrance additives, etc., which contribute greatly to enriching the variety of fine chemical products and improving product quality.
What are the physical properties of 1- (1-bromoethyl) -3- (trifluoromethyl) benzene?
The physical properties of 1- (1-hydroxyethyl) -3- (triethylamino) quinine are those that can be observed externally. This material has specific characteristics such as shape, melting, density and solubility.
First of all, its shape is often liquid. Because of the molecular force, it does not cause the formation of a solid crystal lattice, nor is it easy to melt. Its liquid fluidity is good, so it is easy to pour and mix during the melting operation.
In terms of melting and boiling, due to the molecular temperature and Vander force, the melting temperature is low, often near the usual temperature, and it is easy to melt. The boiling phase is high, and a certain amount of energy is required to vaporize it. This property makes it possible to obtain the product by steaming according to its boiling difference.
In terms of density, water is slightly larger, and it often resides in the coexistence system of water and liquid. This property can be used in liquid-liquid separation operations.
Solubility is also important for physical properties. It can be soluble in many kinds of water, such as ethanol, ether, etc., because its molecules are soluble. However, its solubility in water is limited because of its large base, which weakens the ability of water to form water.
1- (1-hydroxyethyl) -3- (triethylamino) quinine has the physical properties of liquid solution, specific boiling solution, high density and specific solubility, which are important for chemical synthesis, fractionation and application.
Is 1- (1-bromoethyl) -3- (trifluoromethyl) benzene chemically stable?
Whether the chemical properties of 1- (1-hydroxyethyl) -3- (triethylamino) silicon are stable is a key question related to the characteristics of chemical substances. The stability of this substance needs to be analyzed in detail from its molecular structure, chemical bond energy and many other aspects.
In terms of its molecular structure, 1- (1-hydroxyethyl) -3- (triethylamino) silicon, hydroxyethyl is connected to silicon atoms, and triethylamino is also related to silicon atoms. The hydroxyl group in the hydroxyethyl group has certain activity and can participate in many chemical reactions, such as esterification reactions. And triethylamino, as a nitrogenous organic group, also has specific chemical activities.
Looking at its chemical bond energy, the strength of silicon-carbon bonds, silicon-nitrogen bonds and other chemical bonds has a great influence on its stability. If the chemical bond energy is high, more energy is required to break it, and the material stability is relatively high; conversely, if the chemical bond energy is low, the material is relatively active and the stability is poor.
However, only from the theoretical analysis of structure and bond energy is not enough to conclusively determine its stability. In practice, external environmental factors, such as temperature, humidity, light, and the presence or absence of catalysts, all have a significant impact on its chemical stability. In a high-temperature environment, the thermal motion of molecules intensifies, and chemical bonds are more likely to break, resulting in a decrease in material stability; in a high-humidity environment, water molecules may react with the substance, which also affects its stability.
In summary, in order to accurately determine the chemical stability of 1- (1-hydroxyethyl) -3- (triethylamino) silicon, it is necessary to consider its own molecular structure and chemical bond energy, and to fully consider the role of external environmental factors. After comprehensive and comprehensive research, relatively accurate conclusions can be drawn.
What are the synthesis methods of 1- (1-bromoethyl) -3- (trifluoromethyl) benzene?
There are several methods for synthesizing 1- (1-hydroxyethyl) -3- (triethyl) benzene.
One method is to first take an appropriate starting material, such as a benzene compound containing a specific substituent, and use it as a base. After halogenation, a halogen atom is introduced into a specific position on the benzene ring to obtain a halogenated benzene derivative. Then, the halogen and the hydroxyethyl-containing reagent are reacted with a nucleophilic substitution reaction under suitable catalyst and reaction conditions, and the hydroxyethyl group can be connected to the benzene ring. This process requires fine regulation of the reaction temperature, pressure and catalyst dosage to make the reaction proceed smoothly and reduce the occurrence of side reactions. After the hydroxyethyl group is successfully integrated, the product and the reagent containing triethyl group undergo another round of substitution or addition reaction in a specific reaction environment to introduce triethyl group, and finally obtain the target product 1- (1-hydroxyethyl) -3- (triethyl) benzene.
The second method can start with the compound containing triethyl group, and make it with the active benzene ring derivative. Under specific reaction conditions, triethyl group is first introduced into the benzene ring through a process such as Fu-gram reaction. Subsequently, for another position on the benzene ring, a suitable hydroxyethyl-containing reagent is selected, and hydroxyethyl is added through a specific reaction path, such as under the assistance of a suitable alkaline environment and catalyst, by means of nucleophilic substitution, etc., so as to achieve the synthesis of 1- (1-hydroxyethyl) -3- (triethyl) benzene.
Another method can be designed to use a certain type of bifunctional compound as the key intermediate. The bifunctional group is first synthesized, so that one end of the functional group can be connected to the benzene ring in a specific reaction, and some target substituents are introduced, such as triethyl related structures; then, the activity of the other end of the functional group is used to react with the reagent containing hydroxyethyl in the subsequent reaction, and hydroxyethyl is introduced. After careful planning and implementation of the multi-step reaction, 1- (1-hydroxyethyl) -3- (triethyl) benzene can be obtained.
Various synthesis methods have their own advantages and disadvantages. In practical application, it is necessary to weigh and choose according to the availability of raw materials, the ease of control of reaction conditions, and the purity requirements of the product.
What are the precautions for storing and transporting 1- (1-bromoethyl) -3- (trifluoromethyl) benzene?
1 - (1 - hydroxyethyl) - 3 - (triethylamino) silicon should pay attention to the following matters during storage and transportation:
First, the storage place should be selected in a cool and dry place, away from fire and heat sources. Because the substance may be flammable, if it encounters an open flame or hot topic, it may cause the risk of combustion. If the storage environment temperature is too high, or its chemical properties are unstable, accelerated deterioration, and even dangerous reactions may occur.
Second, be sure to ensure the sealing of the storage container. If the seal is not good, the substance is easy to contact with moisture, oxygen and other components in the air. Contact with water, or cause hydrolysis reaction, causing its structure and properties to change, affecting the use efficiency; contact with oxygen, or oxidation reaction, will also have adverse effects on its quality.
Third, during transportation, the container should be properly fixed to prevent collision and dumping. Because it is a chemical product, if the container is damaged during transportation, the material leaks, or poses a threat to the safety of transporters, it may also pollute the surrounding environment.
Fourth, during transportation and storage, it is necessary to strictly avoid mixing and mixing with strong oxidants, strong acids, strong bases and other substances. The chemical properties of the substance determine that it encounters these substances, and it is very likely to have violent chemical reactions, such as explosions, release of toxic gases and other serious consequences.
Fifth, whether it is a storage site or a transportation vehicle, it should be equipped with corresponding fire and leakage emergency treatment equipment. In the event of a fire or leakage accident, it can quickly and effectively respond to reduce losses and hazards. And relevant operators should be familiar with emergency treatment methods and procedures.